Cholesterol reduction by immunization with a PCSK9 mimic

Zhang, B., Chuang, G.-Y., Biju, A., Biner, D., Cheng, J., Wang, Y., Bao, S., Chao, C. W., Lei, H., Liu, T., Nazzari, A. F., Yang, Y., Zhou, T., Chen, S. J., Chen, X., Kong, W.-P., Ou, L., Parchment, D. K., Sarfo, E. K., … Kwong, P. D. (2024). Cholesterol reduction by immunization with a PCSK9 mimic. Cell Reports, 43(6), 114285. https://doi.org/10.1016/j.celrep.2024.114285
Authors:
Baoshan Zhang
Gwo-Yu Chuang
Andrea Biju
Daniel Biner
Jiaxuan Cheng
Yiran Wang
Saran Bao
Cara W Chao
Haotian Lei
Tracy Liu
Alexandra F Nazzari
Yongping Yang
Tongqing Zhou
Steven J Chen
Xuejun Chen
Wing-Pui Kong
Li Ou
Danealle K Parchment
Edward K Sarfo
HaoMin SiMa
John-Paul Todd
Shuishu Wang
Ruth A Woodward
Cheng Cheng
Reda Rawi
John R Mascola
Peter D Kwong
Affiliated Authors:
Peter D Kwong
Columbia Affiliation:
Subjects:
Proprotein Convertase 9 (MeSH)
Cholesterol (MeSH)
Immunization (MeSH)
Macaca fascicularis (MeSH)
Author Keywords:
cholesterol
cp: immunology
cp: metabolism
half-life
immunogen design
low-density lipoprotein
pcsk9
proprotein convertase subtilisin/kexin type 9
vaccine
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.114285
PMID:
38819987
DOI:
10.1016/j.celrep.2024.114285
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: