Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930

Nadezhdin, K. D., Correia, L., Shalygin, A., Aktolun, M., Neuberger, A., Gudermann, T., Kurnikova, M. G., Chubanov, V., & Sobolevsky, A. I. (2024). Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Reports, 43(4), 114108. https://doi.org/10.1016/j.celrep.2024.114108
Authors:
Kirill D Nadezhdin
Leonor Correia
Alexey Shalygin
Muhammed Aktolun
Arthur Neuberger
Thomas Gudermann
Maria G Kurnikova
Vladimir Chubanov
Alexander I Sobolevsky
Affiliated Authors:
Kirill D Nadezhdin
Arthur Neuberger
Alexander I Sobolevsky
Columbia Affiliation:
Subjects:
TRPM Cation Channels (MeSH)
Antineoplastic Agents (MeSH)
1-Naphthylamine (MeSH)
Author Keywords:
cct128930
cp: molecular biology
trp channel
trpm7
calcium
cancer
cryo-em
drug
inhibitor
lipids
magnesium
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.114108
PMID:
38615321
DOI:
10.1016/j.celrep.2024.114108
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: