Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors

Karagiannis, D., Wu, W., Li, A., Hayashi, M., Chen, X., Yip, M., Mangipudy, V., Xu, X., Sánchez-Rivera, F. J., Soto-Feliciano, Y. M., Ye, J., Papagiannakopoulos, T., & Lu, C. (2024). Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors. Cell Reports, 43(1), 113629. https://doi.org/10.1016/j.celrep.2023.113629
Authors:
Dimitris Karagiannis
Warren Wu
Albert P. Li
Makiko Hayashi
Xiao Chen
Michaela Yip
Vaibhav S. Mangipudy
Xinjing Xu
Francisco J. Sánchez‐Rivera
Yadira M. Soto‐Feliciano
Jiangbin Ye
Thales Papagiannakopoulos
Chao Lü
Affiliated Authors:
Dimitris Karagiannis
Xiao Chen
Michaela Yip
Vaibhav S. Mangipudy
Xinjing Xu
Chao Lü
Columbia Affiliation:
Subjects:
Neoplasms (MeSH)
NF-E2-Related Factor 2 (MeSH)
Role of Histone Deacetylases in Cellular Regulation (OpenAlex Topic)
Role of Nrf2 Signaling in Oxidative Stress Response (OpenAlex Topic)
Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)
Author Keywords:
cancer epigenetics
cancer metabolism
cancer targeted therapy
cp: cancer
epigenetic reprogramming
hdac inhibitors
lung cancer
nrf2 pathway
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Publication Type:
Article
Unique ID:
10.1016/j.celrep.2023.113629
PMID:
38165806
DOI:
10.1016/j.celrep.2023.113629
Journal:
Cell Reports
Publication Date:
Data Source:
OpenAlex
Source Link:
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