The AD tau core spontaneously self-assembles and recruits full-length tau to filaments

Carlomagno, Y., Manne, S., DeTure, M., Prudencio, M., Zhang, Y.-J., Hanna Al-Shaikh, R., Dunmore, J. A., Daughrity, L. M., Song, Y., Castanedes-Casey, M., Lewis-Tuffin, L. J., Nicholson, K. A., Wszolek, Z. K., Dickson, D. W., Fitzpatrick, A. W. P., Petrucelli, L., & Cook, C. N. (2021). The AD tau core spontaneously self-assembles and recruits full-length tau to filaments. Cell Reports, 34(11), 108843. https://doi.org/10.1016/j.celrep.2021.108843
Authors:
Yari Carlomagno
Sireesha Manne
Michael DeTure
Mercedes Prudencio
Yong-Jie Zhang
Rana Hanna Al-Shaikh
Judith A Dunmore
Lillian M Daughrity
Yuping Song
Monica Castanedes-Casey
Laura J Lewis-Tuffin
Katharine A Nicholson
Zbigniew K Wszolek
Dennis W Dickson
Anthony W P Fitzpatrick
Leonard Petrucelli
Casey N Cook
Affiliated Authors:
Anthony W P Fitzpatrick
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
tau Proteins (MeSH)
Author Keywords:
aggregation
alzheimer's disease
biomarker
corticobasal degeneration
filament core
neurofibrillary tangles
pick's disease
real-time quaking-induced conversion
tau
tauopathy
Grants:
U01NS110438 (NIH – National Institute of Neurological Disorders and Stroke)
U54NS100693 (NIH – National Institute of Neurological Disorders and Stroke)
R35NS097273 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG063780 (NIH – National Institute On Aging)
RF1AG062171 (NIH – National Institute On Aging)
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Publication Type:
Article
Unique ID:
10.1016/j.celrep.2021.108843
PMID:
33730588
DOI:
10.1016/j.celrep.2021.108843
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record
View Scopus Record

Record Created:

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