Glioma progression is shaped by genetic evolution and microenvironment interactions

Varn, F. S., Johnson, K. C., Martinek, J., Huse, J. T., Nasrallah, M. P., Wesseling, P., Cooper, L. A. D., Malta, T. M., Wade, T. E., Sabedot, T. S., Brat, D., Gould, P. V., Wöehrer, A., Aldape, K., Ismail, A., Sivajothi, S. K., Barthel, F. P., Kim, H., Kocakavuk, E., … Verhaak, R. GW. (2022). Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell, 185(12), 2184-2199.e16. https://doi.org/10.1016/j.cell.2022.04.038
Authors:
Frederick S Varn
Kevin C Johnson
Jan Martinek
Jason T Huse
MacLean P Nasrallah
Pieter Wesseling
Lee A D Cooper
Tathiane M Malta
Taylor E Wade
Thais S Sabedot
Daniel Brat
Peter V Gould
Adelheid Wöehrer
Kenneth Aldape
Azzam Ismail
Santhosh K Sivajothi
Floris P Barthel
Hoon Kim
Emre Kocakavuk
Nazia Ahmed
Kieron White
Indrani Datta
Hyo-Eun Moon
Steven Pollock
Christine Goldfarb
Ga-Hyun Lee
Luciano Garofano
Kevin J Anderson
Djamel Nehar-Belaid
Jill S Barnholtz-Sloan
Spyridon Bakas
Annette T Byrne
Fulvio D'Angelo
Hui K Gan
Mustafa Khasraw
Simona Migliozzi
D Ryan Ormond
Sun Ha Paek
Erwin G Van Meir
Annemiek M E Walenkamp
Colin Watts
Tobias Weiss
Michael Weller
Karolina Palucka
Lucy F Stead
Laila M Poisson
Houtan Noushmehr
Antonio Iavarone
Roel G W Verhaak
Affiliated Authors:
Luciano Garofano
Fulvio D'Angelo
Simona Migliozzi
Antonio Iavarone
Columbia Affiliation:
Subjects:
Gliomas (OpenAlex Topic)
Comprehensive Integration of Single-Cell Transcriptomic Data (OpenAlex Topic)
MicroRNA Regulation in Cancer and Development (OpenAlex Topic)
Brain Neoplasms (MeSH)
Glioma (MeSH)
Tumor Microenvironment (MeSH)
Author Keywords:
genomics
glioblastoma
glioma
hypermutation
macrophages
microenvironment
neurons
single-cell
spatial imaging
treatment resistance
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Publication Type:
Article
Unique ID:
10.1016/j.cell.2022.04.038
PMID:
35649412
DOI:
10.1016/j.cell.2022.04.038
Journal:
Cell
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: