NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer

Salomé, B., Sfakianos, J. P., Ranti, D., Daza, J., Bieber, C., Charap, A., Hammer, C., Banchereau, R., Farkas, A. M., Ruan, D. F., Izadmehr, S., Geanon, D., Kelly, G., de Real, R. M., Lee, B., Beaumont, K. G., Shroff, S., Wang, Y. A., Wang, Y., … Horowitz, A. (2022). NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer. Cancer Cell, 40(9), 1027-1043.e9. https://doi.org/10.1016/j.ccell.2022.08.005
Authors:
Bérengère Salomé
John P Sfakianos
Daniel Ranti
Jorge Daza
Christine Bieber
Andrew Charap
Christian Hammer
Romain Banchereau
Adam M Farkas
Dan Fu Ruan
Sudeh Izadmehr
Daniel Geanon
Geoffrey Kelly
Ronaldo M de Real
Brian Lee
Kristin G Beaumont
Sanjana Shroff
Yuanshuo A Wang
Ying-Chih Wang
Tin Htwe Thin
Monica Garcia-Barros
Everardo Hegewisch-Solloa
Emily M Mace
Li Wang
Timothy O'Donnell
Diego Chowell
Ruben Fernandez-Rodriguez
Mihaela Skobe
Nicole Taylor
Seunghee Kim-Schulze
Robert P Sebra
Doug Palmer
Eleanor Clancy-Thompson
Scott Hammond
Alice O Kamphorst
Karl-Johan Malmberg
Emanuela Marcenaro
Pedro Romero
Rachel Brody
Mathias Viard
Yuko Yuki
Maureen Martin
Mary Carrington
Reza Mehrazin
Peter Wiklund
Ira Mellman
Sanjeev Mariathasan
Jun Zhu
Matthew D Galsky
Nina Bhardwaj
Amir Horowitz
Affiliated Authors:
Everardo Hegewisch-Solloa
Emily M Mace
Columbia Affiliation:
Subjects:
NK Cell Lectin-Like Receptor Subfamily C (MeSH)
Urinary Bladder Neoplasms (MeSH)
Author Keywords:
bladder cancer
cd8 t cells
checkpoint blockade immunotherapy
hla class i
immune exhaustion
nk cells
nkg2a
solid tumors
tumor microenvironment
cd8 t cells
elink
Publication Type:
Article
Unique ID:
10.1016/j.ccell.2022.08.005
PMID:
36099881
DOI:
10.1016/j.ccell.2022.08.005
Journal:
Cancer Cell
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: