The Sixth Sense: Self-nucleic acid sensing in the brain

Dorrity, T. J., Shin, H., Gertie, J. A., & Chung, H. (2024). The Sixth Sense: Self-nucleic acid sensing in the brain. Nucleic Acid Associated Mechanisms in Immunity and Disease, 53–83. https://doi.org/10.1016/bs.ai.2024.03.001
Authors:
Tyler J Dorrity
Heegwon Shin
Jake A Gertie
Hachung Chung
Affiliated Authors:
Tyler J Dorrity
Heegwon Shin
Jake A Gertie
Hachung Chung
Columbia Affiliation:
Subjects:
Brain (MeSH)
Receptors, Pattern Recognition (MeSH)
Immunity, Innate (MeSH)
Nucleic Acids (MeSH)
Author Keywords:
brain
dna sensing prrs: cgas, aim2, tlr9
neurodegeneration: aicardi-goutieres syndrome (ags), alzheimer's disease, amyotrophic lateral sclerosis, stroke, traumatic brain injury
neurodevelopment
neuroinflammation
nuecleic acid immunity
pattern recognition receptors (prrs)
rna sensing prrs: mda5, rig-i, pkr, tlr3, tlr7/8
elink
Publication Type:
Article
Unique ID:
10.1016/bs.ai.2024.03.001
PMID:
38763702
DOI:
10.1016/bs.ai.2024.03.001
Journal:
Advances in Immunology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: