Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease

Chen, C. D., McCullough, A., Gordon, B., Joseph-Mathurin, N., Flores, S., McKay, N. S., Hobbs, D. A., Hornbeck, R., Fagan, A. M., Cruchaga, C., Goate, A. M., Perrin, R. J., Wang, G., Li, Y., Shi, X., Xiong, C., Pontecorvo, M. J., Klein, G., … Su, Y. (2023). Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging, 50(9), 2669–2682. https://doi.org/10.1007/s00259-023-06209-0
Authors:
Charles D Chen
Austin McCullough
Brian Gordon
Nelly Joseph-Mathurin
Shaney Flores
Nicole S McKay
Diana A Hobbs
Russ Hornbeck
Anne M Fagan
Carlos Cruchaga
Alison M Goate
Richard J Perrin
Guoqiao Wang
Yan Li
Xinyu Shi
Chengjie Xiong
Michael J Pontecorvo
Gregory Klein
Yi Su
William E Klunk
Clifford Jack
Robert Koeppe
B Joy Snider
Sarah B Berman
Erik D Roberson
Jared Brosch
Ghulam Surti
Ivonne Z Jiménez-Velázquez
Douglas Galasko
Lawrence S Honig
William S Brooks
Roger Clarnette
David Wallon
Bruno Dubois
Jérémie Pariente
Florence Pasquier
Raquel Sanchez-Valle
Sergey Shcherbinin
Ixavier Higgins
Ilke Tunali
Colin L Masters
Christopher H van Dyck
Mario Masellis
Robin Hsiung
Serge Gauthier
Steve Salloway
David B Clifford
Susan Mills
Charlene Supnet-Bell
Eric McDade
Randall J Bateman
Tammie L S Benzinger
Affiliated Authors:
Lawrence S Honig
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Author Keywords:
18f-florbetapir
dominantly inherited alzheimer’s disease
gantenerumab
pittsburgh compound b
Grants:
K01AG080123 (NIH – National Institute On Aging)
P30AG066462 (NIH – National Institute On Aging)
P30AG066508 (NIH – National Institute On Aging)
P30AG072980 (NIH – National Institute On Aging)
P30NS098577 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG046179 (NIH – National Institute On Aging)
R01AG052550 (NIH – National Institute On Aging)
R01AG053267 (NIH – National Institute On Aging)
R01AG068319 (NIH – National Institute On Aging)
S10OD025214 (NIH – Office of the Director, National Institutes of Health)
T32AG058518 (NIH – National Institute On Aging)
U01AG042791 (NIH – National Institute On Aging)
U19AG032438 (NIH – National Institute On Aging)
UF1AG032438 (NIH – National Institute On Aging)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
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Publication Type:
Article
Unique ID:
10.1007/s00259-023-06209-0
PMID:
37017737
DOI:
10.1007/s00259-023-06209-0
Journal:
European Journal of Nuclear Medicine and Molecular Imaging
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

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