Does white matter and vascular injury from repetitive head impacts lead to a novel pattern on T2 FLAIR MRI? A hypothesis proposal and call for research

Miner, A. E., Groh, J. R., Farris, C., Hattiangadi, S., Cui, A., Brickman, A. M., Alshikho, M., Rabinovici, G. D., Rosen, H. J., Cobigo, Y., Asken, B., Nowinski, C. J., Bureau, S., Shahrokhi, F., Tripodis, Y., Ly, M., Altaras, C., Lenio, S., Stern, R. A., … Alosco, M. L. (2025). Does white matter and vascular injury from repetitive head impacts lead to a novel pattern on T2 FLAIR MRI? A hypothesis proposal and call for research. Alzheimer’s & Dementia, 21(3). Portico. https://doi.org/10.1002/alz.70085
Authors:
Annalise E Miner
Jenna R Groh
Chad Farris
Sarina Hattiangadi
Anna Cui
Adam M Brickman
Mohamad Alshikho
Gil D Rabinovici
Howie J Rosen
Yann Cobigo
Breton Asken
Christopher J Nowinski
Samantha Bureau
Fereydoun Shahrokhi
Yorghos Tripodis
Monica Ly
Caroline Altaras
Steven Lenio
Robert A Stern
Grace Rosen
Hunter Kelley
Bertrand Russell Huber
Thor D Stein
Jesse Mez
Ann C McKee
Michael L Alosco
Affiliated Authors:
Adam M Brickman
Mohamad Alshikho
Columbia Affiliation:
Subjects:
White Matter (MeSH)
Magnetic Resonance Imaging (MeSH)
Author Keywords:
flair mri
rhi‐wmh
chronic traumatic encephalopathy
contact and collision sports
fluid attenuated inversion recovery neuroimaging biomarkers
head trauma
neurodegenerative disease
repetitive head impacts
repetitive head impact‐associated white matter hyperintensities
traumatic brain injury
traumatic encephalopathy syndrome
white matter hyperintensities
elink
Publication Type:
Article
Unique ID:
10.1002/alz.70085
PMID:
40145364
DOI:
10.1002/alz.70085
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: