The ATM Kinase Inhibitor AZD0156 is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and is an Attractive Candidate for Medicinal Chemistry Optimisation Ag…

Woodland, J. G., Coertzen, D., Wicht, K. J., Hidalgo, V. F., Pasaje, C. F. A., Godoy, L. C., Qahash, T., Mmonwa, M. M., Dziwornu, G. A., Wambua, L., Harries, S., Korkor, C. M., Njoroge, M., Krugmann, L., Taylor, D., Leshabane, M., Langeveld, H., Rabie, T., Reader, J., … Chibale, K. (2025). The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria. Angewandte Chemie. Portico. https://doi.org/10.1002/ange.202425206
Authors:
John G. Woodland
Dina Coertzen
Kathryn J. Wicht
Virginia Franco Hidalgo
Charisse Flerida A. Pasaje
Luiz C. Godoy
Tarrick Qahash
Mmakwena Modlicious Mmonwa
Godwin Akpeko Dziwornu
Lynn Wambua
Sarah Harries
Constance M. Korkor
Mathew Njoroge
Liezl Gibhard
Dale Taylor
Meta Leshabane
Henrico Langeveld
Tayla Rabie
Janette Reader
Mariëtte van der Watt
Nelius Venter
Erica Erlank
Ayesha S. Aswat
Lizette L. Koekemoer
Tomas Yeo
Jin Yong Jeon
David A. Fidock
Francisco‐Javier Gamo
Sergio Wittlin
Jacquin C. Niles
Manuel Llinás
Lauren B. Coulson
Lyn‐Marié Birkholtz
Kelly Chibale
Affiliated Authors:
Tomas Yeo
Jin Yong Jeon
David A. Fidock
Columbia Affiliation:
Subjects:
Efficacy and Resistance in CML Treatment (OpenAlex Topic)
Genomic Aberrations and Treatment of Chronic Lymphocytic Leukemia (OpenAlex Topic)
Synthesis and Characterization of Heterocyclic Compounds (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1002/ange.202425206
DOI:
10.1002/ange.202425206
Journal:
Angewandte Chemie
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record

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