hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome

Zhou, D., Feng, H., Yang, Y., Huang, T., Qiu, P., Zhang, C., Olsen, T. R., Zhang, J., Chen, Y. E., Mizrak, D., & Yang, B. (2021). hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1 A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome. Circulation, 144(14), 1145–1159. https://doi.org/10.1161/circulationaha.121.054744
Authors:
Dong Zhou
Hao Feng
Ying Yang
Tingting Huang
Ping Qiu
Y. Eugene Chen
Dogukan Mizrak
Bo Yang
Chengxin Zhang
Jifeng Zhang
Timothy R. Olsen
Affiliated Authors:
Timothy R. Olsen
Author Keywords:
activins
hipsc
loeys-dietz syndrome
rapamycin
rna sequencing
smooth muscle cells
tgfbr1
Publication Type:
Article
Unique ID:
10.1161/CIRCULATIONAHA.121.054744
PMID:
Journal:
Publication Date:
Data Source:
Web of Science

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