Polyclonality Strongly Correlates with Biological Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of LentiGlobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT)

Tisdale, J. F., Thompson, A. A., Mapara, M. Y., Kwiatkowski, J. L., Krishnamurti, L., Aygun, B., Kasow, K. A., Rifkin-Zenenberg, S., Schmidt, M., Pierciey, F. J., Whitney, D., Rogers, C., Nnamani, M., Foos, M., Miller, A., Zhang, X., Lynch, J., Walters, M. C., Kanter, J., & Bonner, M. (2021). Polyclonality Strongly Correlates with Biological Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of LentiGlobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT). Blood, 138(Supplement 1), 561–561. https://doi.org/10.1182/blood-2021-147760
Authors:
John F. Tisdale
Alexis A. Thompson
Markus Y. Mapara
Janet L. Kwiatkowski
Lakshmanan Krishnamurti
Banu Aygün
Kimberly A. Kasow
Stacey Rifkin-Zenenberg
Manfred Schmidt
Francis J. Pierciey
Dustin Whitney
Cynthia Rogers
Mauris C. Nnamani
Marianna Foos
Alex Miller
Xinyan Zhang
Jessie Lynch
Mark C. Walters
Julie Kanter
Melissa Bonner
Affiliated Authors:
Markus Y. Mapara
Publication Type:
Article
Unique ID:
10.1182/blood-2021-147760
Journal:
Publication Date:
Data Source:
OpenAlex

Record Created: