Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation

Sheng, Z., Bimela, J. S., Katsamba, P. S., Patel, S. D., Guo, Y., Zhao, H., Guo, Y., Kwong, P. D., & Shapiro, L. (2022). Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.811632
Authors:
Zizhang Sheng
Jude S Bimela
Phinikoula S Katsamba
Saurabh D Patel
Yicheng Guo
Haiqing Zhao
Youzhong Guo
Peter D Kwong
Lawrence Shapiro
Affiliated Authors:
Zizhang Sheng
Jude S Bimela
Phinikoula S Katsamba
Saurabh D Patel
Yicheng Guo
Haiqing Zhao
Peter D Kwong
Lawrence Shapiro
Columbia Affiliation:
Subjects:
Antibodies (MeSH)
Antibody Affinity (MeSH)
HIV Antibodies (MeSH)
Molecular Dynamics Simulation (MeSH)
Author Keywords:
antibody
broadly hiv-1 neutralizing antibody
conformation modulation
epistasis
indel
molecular dynamics simulation
somatic hypermutation
stability
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Publication Type:
Article
Unique ID:
10.3389/fimmu.2021.811632
PMID:
35046963
DOI:
10.3389/fimmu.2021.811632
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: