Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

Longchamps, R. J., Yang, S. Y., Castellani, C. A., Shi, W., Lane, J., Grove, M. L., Bartz, T. M., Sarnowski, C., Liu, C., Burrows, K., Guyatt, A. L., Gaunt, T. R., Kacprowski, T., Yang, J., De Jager, P. L., Yu, L., Bergman, A., Xia, R., Fornage, M., … Arking, D. E. (2021). Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Human Genetics, 141(1), 127–146. https://doi.org/10.1007/s00439-021-02394-w
Authors:
R.J. Longchamps
S.Y. Yang
C.A. Castellani
W. Shi
J. Lane
M.L. Grove
T.M. Bartz
C. Sarnowski
C. Liu
K. Burrows
A.L. Guyatt
T.R. Gaunt
T. Kacprowski
J. Yang
P.L. De Jager
L. Yu
A. Bergman
R. Xia
M. Fornage
M.F. Feitosa
M.K. Wojczynski
A.T. Kraja
M.A. Province
N. Amin
F. Rivadeneira
H. Tiemeier
A.G. Uitterlinden
L. Broer
J.B.J. Van Meurs
C.M. Van Duijn
L.M. Raffield
L. Lange
S.S. Rich
R.N. Lemaitre
M.O. Goodarzi
C.M. Sitlani
A.C.Y. Mak
D.A. Bennett
S. Rodriguez
J.M. Murabito
K.L. Lunetta
N. Sotoodehnia
G. Atzmon
K. Ye
N. Barzilai
J.A. Brody
B.M. Psaty
K.D. Taylor
J.I. Rotter
E. Boerwinkle
N. Pankratz
D.E. Arking
Affiliated Authors:
P.L. De Jager
Columbia Affiliation:
Subjects:
Mitochondrial Dynamics and Reactive Oxygen Species Regulation (OpenAlex Topic)
Metabolic Disorders and Biochemical Genetics (OpenAlex Topic)
Peroxisome Proliferator-Activated Receptors (OpenAlex Topic)
Megakaryocytes (MeSH)
Mitochondria (MeSH)
DNA Copy Number Variations (MeSH)
DNA, Mitochondrial (MeSH)
Platelet Activation (MeSH)
Polymorphism, Single Nucleotide (MeSH)
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Publication Type:
Article
Unique ID:
10.1007/s00439-021-02394-w
PMID:
34859289
DOI:
10.1007/s00439-021-02394-w
Journal:
Human Genetics
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
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View OpenAlex Record
View Web of Science Record

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