Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

Gurtan, A., Dominy, J., Khalid, S., Vong, L., Caplan, S., Currie, T., Richards, S., Lamarche, L., Denning, D., Shpektor, D., Gurinovich, A., Rasheed, A., Hameed, S., Saeed, S., Saleem, I., Jalal, A., Abbas, S., Sultana, R., Rasheed, S. Z., … Saleheen, D. (2022). Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index. PLOS Genetics, 18(4), e1010093. https://doi.org/10.1371/journal.pgen.1010093
Authors:
Allan Gurtan
John Dominy
Shareef Khalid
Linh Vong
Shari L. Caplan
Treeve Currie
Sean Richards
Lindsey B. Lamarche
Daniel P. Denning
Diana Shpektor
Anastasia Gurinovich
Asif Rasheed
Shahid Hameed
Subhan Saeed
Imran Saleem
Anjum Jalal
Shahid Abbas
Raffat Sultana
Syed Zahed Rasheed
Fazal-ur-Rehman Memon
Nabi Shah
Mohammad Ishaq
Amit V. Khera
John Danesh
Philippe Frossard
Danish Saleheen
Affiliated Authors:
Shareef Khalid
Danish Saleheen
Columbia Affiliation:
Subjects:
Diabetes Mellitus, Type 2 (MeSH)
Receptors, G-Protein-Coupled (MeSH)
Structure and Function of G Protein-Coupled Receptors (OpenAlex Topic)
Management of Diabetes Mellitus and Cardiovascular Risk (OpenAlex Topic)
Role of Neuropeptides in Physiology and Disease (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1371/journal.pgen.1010093
PMID:
35381001
DOI:
10.1371/journal.pgen.1010093
Journal:
PLOS Genetics
Publication Date:
Data Source:
OpenAlex
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