Isolation and structure of broad SIV-neutralizing antibodies reveal a proximal helical MPER epitope recognized by a rhesus multi-donor class

Gorman, J., Du, R., Lai, Y.-T., Ahmadi, M. S., King, H. A. D., Song, K., Manalang, K., Gonelli, C. A., Schramm, C. A., Cheng, C., Nguyen, R., Ambrozak, D., Druz, A., Shen, C.-H., Yang, Y., Douek, D. C., Kwong, P. D., Roederer, M., & Mason, R. D. (2025). Isolation and structure of broad SIV-neutralizing antibodies reveal a proximal helical MPER epitope recognized by a rhesus multi-donor class. Cell Reports, 44(1), 115163. https://doi.org/10.1016/j.celrep.2024.115163
Authors:
Jason Gorman
Renguang Du
Yen-Ting Lai
Mohammed S Ahmadi
Hannah A D King
Kaimei Song
Kimberly Manalang
Christopher A Gonelli
Chaim A Schramm
Cheng Cheng
Richard Nguyen
David Ambrozak
Aliaksandr Druz
Chen-Hsiang Shen
Yongping Yang
Daniel C Douek
Peter D Kwong
Mario Roederer
Rosemarie D Mason
Affiliated Authors:
Peter D Kwong
Columbia Affiliation:
Subjects:
Macaca mulatta (MeSH)
Simian Immunodeficiency Virus (MeSH)
Epitopes (MeSH)
Antibodies, Neutralizing (MeSH)
Simian Acquired Immunodeficiency Syndrome (MeSH)
Author Keywords:
broadly neutralizing antibody
cp: immunology
gp41
hiv-1
membrane-proximal external region
mper
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.115163
PMID:
39792559
DOI:
10.1016/j.celrep.2024.115163
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: