Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer

Myer, P. A., Kim, H., Blümel, A. M., Finnegan, E., Kel, A., Thompson, T. V., Greally, J. M., Prehn, J. HM., O’Connor, D. P., Friedman, R. A., Floratos, A., & Das, S. (2022). Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer. Gastro Hep Advances, 1(3), 328–341. https://doi.org/10.1016/j.gastha.2022.01.004
Authors:
Parvathi A Myer
Hyunjin Kim
Anna M Blümel
Ellen Finnegan
Alexander Kel
Taylor V Thompson
John M Greally
Jochen Hm Prehn
Darran P O'Connor
Richard A Friedman
Aris Floratos
Sudipto Das
Affiliated Authors:
Richard A Friedman
Aris Floratos
Columbia Affiliation:
Subjects:
Molecular Characterization of Colorectal Cancer (OpenAlex Topic)
Role of Long Noncoding RNAs in Cancer and Development (OpenAlex Topic)
Mechanisms and Implications of Ferroptosis in Cancer (OpenAlex Topic)
Author Keywords:
african americans.
colorectal cancer
genomic profiling
health disparities
afr, african
cma, composite module analyst
crc, colorectal cancer
champ, chip analysis methylation pipeline
degs, differentially expressed genes
dmps, differentially methylated cpg positions
eur, european
fdr, false discovery rate
mcp, microenvironment cell population
msi-h, microsatellite high
msi-l, microsatellite low
mss, microsatellite stable
mtrs, master transcriptional regulators
tcga, the cancer genome atlas
tfbs, tf binding site
tfs, transcription factors
tmb, tumor mutation burden
tss, transcription start site
elink
Publication Type:
Article
Unique ID:
10.1016/j.gastha.2022.01.004
PMID:
35711675
DOI:
10.1016/j.gastha.2022.01.004
Journal:
Gastro Hep Advances
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record
View Scopus Record

Record Created: