Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results

Palmer, C. D., Rappaport, A. R., Davis, M. J., Hart, M. G., Scallan, C. D., Hong, S.-J., Gitlin, L., Kraemer, L. D., Kounlavouth, S., Yang, A., Smith, L., Schenk, D., Skoberne, M., Taquechel, K., Marrali, M., Jaroslavsky, J. R., Nganje, C. N., Maloney, E., Zhou, R., … Jooss, K. (2022). Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results. Nature Medicine, 28(8), 1619–1629. https://doi.org/10.1038/s41591-022-01937-6
Authors:
Christine D. Palmer
Amy Rappaport
Matthew J. Davis
Meghan G. Hart
Ciaran D. Scallan
Sue-Jean Hong
Leonid Gitlin
Lauren D. Kraemer
Sonia Kounlavouth
Aaron Yang
Lindsey Smith
Desiree Schenk
Mojca Škoberne
Kiara Taquechel
Martina Marrali
Jason R. Jaroslavsky
Charmaine N. Nganje
Elizabeth Maloney
Rita Zhou
Daniel Navarro-Gomez
Adrienne C. Greene
Gijsbert M. Grotenbreg
Renee L. Greer
Wade Blair
Minh Duc Cao
Shawn Chan
Kyounghwa Bae
Alexander I. Spira
Sameek Roychowdhury
David P. Carbone
Brian S. Henick
Charles G. Drake
Benjamin Solomon
Daniel H. Ahn
Amit Mahipal
Steve Maron
Benny Johnson
Raphaël F. Rousseau
Roman Yelensky
Chih‐Yi Liao
Daniel V.T. Catenacci
Andrew M. Allen
Andrew R. Ferguson
Karin Jooss
Affiliated Authors:
Brian S. Henick
Charles G. Drake
Columbia Affiliation:
Subjects:
Colorectal Neoplasms (MeSH)
Pan troglodytes (MeSH)
Immunobiology of Dendritic Cells (OpenAlex Topic)
Chimeric Antigen Receptor T Cell Therapy (OpenAlex Topic)
Cancer Immunotherapy (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41591-022-01937-6
PMID:
35970920
DOI:
10.1038/s41591-022-01937-6
Journal:
Nature Medicine
Publication Date:
Data Source:
OpenAlex
Source Link:
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