De novo design of protein structure and function with RFdiffusion

Watson, J. L., Juergens, D., Bennett, N. R., Trippe, B. L., Yim, J., Eisenach, H. E., Ahern, W., Borst, A. J., Ragotte, R. J., Milles, L. F., Wicky, B. I. M., Hanikel, N., Pellock, S. J., Courbet, A., Sheffler, W., Wang, J., Venkatesh, P., Sappington, I., Torres, S. V., … Baker, D. (2023). De novo design of protein structure and function with RFdiffusion. Nature, 620(7976), 1089–1100. https://doi.org/10.1038/s41586-023-06415-8
Authors:
Joseph L Watson
David Juergens
Nathaniel R Bennett
Brian L Trippe
Jason Yim
Helen E Eisenach
Woody Ahern
Andrew J Borst
Robert J Ragotte
Lukas F Milles
Basile I M Wicky
Nikita Hanikel
Samuel J Pellock
Alexis Courbet
William Sheffler
Jue Wang
Preetham Venkatesh
Isaac Sappington
Susana Vázquez Torres
Anna Lauko
Valentin De Bortoli
Emile Mathieu
Sergey Ovchinnikov
Regina Barzilay
Tommi S Jaakkola
Frank DiMaio
Minkyung Baek
David Baker
Affiliated Authors:
Brian L Trippe
Columbia Affiliation:
Subjects:
Deep Learning (MeSH)
Proteins (MeSH)
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Publication Type:
Article
Unique ID:
10.1038/s41586-023-06415-8
PMID:
37433327
DOI:
10.1038/s41586-023-06415-8
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

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