Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells

Saha, N., Lee, S. G., Brockmann, E.-C., de la Cruz, M. J., Goldgur, Y., Mendoza, R. P., Stanchina, E. de, Love, T. M., Marvald, J., Xu, Y., Xu, K., Himanen, J. P., Lamminmäki, U., Veach, D., & Nikolov, D. B. (2024). Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells. Biomedicine & Pharmacotherapy, 180, 117605. https://doi.org/10.1016/j.biopha.2024.117605
Authors:
Nayanendu Saha
Sang Gyu Lee
Eeva-Christine Brockmann
M Jason de la Cruz
Yehuda Goldgur
Rachelle P Mendoza
Elisa de Stanchina
Tanzy M Love
Josh Marvald
Yan Xu
Kai Xu
Juha P Himanen
Urpo Lamminmäki
Darren Veach
Dimitar B Nikolov
Affiliated Authors:
Rachelle P Mendoza
Author Keywords:
adam17
cryo-electron microscopy
epidermal growth factor
monoclonal antibody
positron emission tomography
xenograft
Publication Type:
Article
Unique ID:
10.1016/j.biopha.2024.117605
PMID:
Publication Date:
Data Source:
PubMed

Record Created: