Oligomeric interactions maintain active-site structure in a noncooperative enzyme family

Li, Y., Zhang, R., Wang, C., Forouhar, F., Clarke, O. B., Vorobiev, S., Singh, S., Montelione, G. T., Szyperski, T., Xu, Y., & Hunt, J. F. (2022). Oligomeric interactions maintain active‐site structure in a noncooperative enzyme family. The EMBO Journal, 41(17). Portico. https://doi.org/10.15252/embj.2021108368
Authors:
Yaohui Li
Rongzhen Zhang
Chi Wang
Farhad Forouhar
Oliver B Clarke
Sergey Vorobiev
Shikha Singh
Gaetano T Montelione
Thomas Szyperski
Yan Xu
John F Hunt
Affiliated Authors:
Yaohui Li
Chi Wang
Farhad Forouhar
Oliver B Clarke
Sergey Vorobiev
Shikha Singh
John F Hunt
Columbia Affiliation:
Subjects:
Macromolecular Crystallography Techniques (OpenAlex Topic)
Protein Structure Prediction and Analysis (OpenAlex Topic)
Nucleotide Metabolism and Enzyme Regulation (OpenAlex Topic)
Biological Evolution (MeSH)
Oxidoreductases (MeSH)
Author Keywords:
cryo-em
enzyme mechanism
oligomeric interactions
protein evolution
short-chain dehydrogenases-reductases
elink
Publication Type:
Article
Unique ID:
10.15252/embj.2021108368
PMID:
35801308
DOI:
10.15252/embj.2021108368
Journal:
EMBO Journal
Publication Date:
Data Source:
PubMed
Source Link:
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Record Created: