The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease

Ribeiro, F. C., Cozachenco, D., Argyrousi, E. K., Staniszewski, A., Wiebe, S., Calixtro, J. D., Soares‐Neto, R., Al‐Chami, A., Sayegh, F. E., Bermudez, S., Arsenault, E., Cossenza, M., Lacaille, J., Nader, K., Sun, H., De Felice, F. G., Lourenco, M. V., Arancio, O., Aguilar‐Valles, A., … Ferreira, S. T. (2024). The ketamine metabolite (2R,6R)‐hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer’s disease. Alzheimer’s & Dementia, 20(8), 5398–5410. Portico. https://doi.org/10.1002/alz.14034
Authors:
Felipe C. Ribeiro
Danielle Cozachenco
Elentina K. Argyrousi
Agnieszka Staniszewski
Shane Wiebe
Joao D. Calixtro
Rubens Soares-Neto
Aycheh Al-Chami
Fatema El Sayegh
Sara Bermudez
Emily Arsenault
Marcelo Cossenza
Jean-Claude Lacaille
Karim Nader
Hongyu Sun
Fernanda G. De Felice
Mychael V. Lourenco
Ottavio Arancio
Argel Aguilar-Valles
Nahum Sonenberg
Sergio T. Ferreira
Affiliated Authors:
Elentina K. Argyrousi
Agnieszka Staniszewski
Ottavio Arancio
Author Keywords:
alzheimer's disease
hydroxynorketamine
mrna translation
memory
synaptic plasticity
alzheimer's disease
Publication Type:
Article
Unique ID:
10.1002/alz.14034
Publication Date:
Data Source:
Scopus

Record Created: