Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice

Lee, Y.-K., Du, W., Nie, Y., Diaz, B., Sultana, N., Kitamoto, T., Leibel, R. L., Accili, D., & Belvedere, S. (2022). Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice. Molecular Metabolism, 66, 101618. https://doi.org/10.1016/j.molmet.2022.101618
Authors:
Yun-Kyoung Lee
Wen Du
Yaohui Nie
Bryan Diaz
Nishat Sultana
Takumi Kitamoto
Rudolph L. Leibel
Domenico Accili
Sandro Belvedere
Affiliated Authors:
Wen Du
Bryan Diaz
Nishat Sultana
Takumi Kitamoto
Rudolph L. Leibel
Domenico Accili
Columbia Affiliation:
Author Keywords:
foxo1 inhibitor
t1d
gut 0-like cells
insulin
glucose lowering effect
gut β-like cells
elink
Publication Type:
Article
Unique ID:
10.1016/j.molmet.2022.101618
PMID:
36283677
DOI:
10.1016/j.molmet.2022.101618
Journal:
Molecular Metabolism
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
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Record Created: