Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers

Kabeer, F., Tran, H., Andronescu, M., Singh, G., Lee, H., Salehi, S., Wang, B., Biele, J., Brimhall, J., Gee, D., Cerda, V., O’Flanagan, C., Algara, T., Kono, T., Beatty, S., Zaikova, E., Lai, D., Lee, E., … Moore, R. (2024). Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers. Genome Biology, 25(1). https://doi.org/10.1186/s13059-024-03318-3
Authors:
Farhia Kabeer
Hoa Tran
Mirela Andronescu
Gurdeep Singh
Hakwoo Lee
Sohrab P. Shah
Beixi Wang
Justina Biele
Jazmine Brimhall
David Gee
Viviana Cerda
Ciara H. O’Flanagan
Teresa Ruiz de Algara
Takako Kono
Sean Beatty
Elena Zaikova
Daniel Lai
Eric Lee
Richard A. Moore
Andrew J. Mungall
Marc Williams
Andrew Roth
Kieran R. Campbell
Sohrab P. Shah
Samuel Aparício
Affiliated Authors:
Sohrab P. Shah
Sohrab P. Shah
Columbia Affiliation:
Subjects:
Triple Negative Breast Neoplasms (MeSH)
Single-Cell Analysis (MeSH)
Transcriptome (MeSH)
Drug Resistance, Neoplasm (MeSH)
Comprehensive Integration of Single-Cell Transcriptomic Data (OpenAlex Topic)
Genomic Landscape of Cancer and Mutational Signatures (OpenAlex Topic)
Cancer Stem Cells and Tumor Metastasis (OpenAlex Topic)
Author Keywords:
pdx
single-cell rna sequencing
dlp plus single-cell sequencing
cisplatin treatment
in-cis/in-trans genes
sensitive/resistant clones
clone aware analysis
dlp+ single-cell sequencing
elink
Publication Type:
Article
Unique ID:
10.1186/s13059-024-03318-3
PMID:
39026273
DOI:
10.1186/s13059-024-03318-3
Journal:
Genome Biology
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: