Molecular Regulation and Clinical Applications of PDEs

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Gomez-Gonzalez, P.-J., Gupta, A., Drought, L. G., Patel, A., Okombo, J., van der Watt, M., Walker-Gray, R., Schindler, K. A., Burkhard, A. Y., Yeo, T., Narwal, S. K., Bloxham, T. S., Flueck, C., Walker, E. M., Rey, J. A., Fairhurst, K. J., Reader, J., Park, H., Pollard, H. G., … Baker, D. A. (2024). Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission. Science Advances, 10(49). https://doi.org/10.1126/sciadv.adq1383
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Colombo, S., Reddy, H. P., Petri, S., Williams, D. J., Shalomov, B., Dhindsa, R. S., Gelfman, S., Krizay, D., Bera, A. K., Yang, M., Peng, Y., Makinson, C. D., Boland, M. J., Frankel, W. N., Goldstein, D. B., & Dascal, N. (2023). Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor. Frontiers in Cellular Neuroscience, 17. https://doi.org/10.3389/fncel.2023.1175895
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