Hepatic Stellate Cells

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Prasad, K., Bhattacharya, D., Shams, S. G. E., Izarraras, K., Hart, T., Mayfield, B., Blaszczyk, M. B., Zhou, Z., Pajvani, U. B., Friedman, S. L., & Bhattacharya, M. (2024). Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFβ Signaling in Hepatic Stellate Cells. Cells, 13(19), 1651. https://doi.org/10.3390/cells13191651
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Fondevila, M. F., Novoa, E., Gonzalez-Rellan, M. J., Fernandez, U., Heras, V., Porteiro, B., Parracho, T., Dorta, V., Riobello, C., da Silva Lima, N., Seoane, S., Garcia-Vence, M., Chantada-Vazquez, M. P., Bravo, S. B., Senra, A., Leiva, M., Marcos, M., Sabio, G., Perez-Fernandez, R., … Nogueiras, R. (2024). p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway. Cell Reports Medicine, 5(2), 101401. https://doi.org/10.1016/j.xcrm.2024.101401
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Chung, K.-J., Legaki, A.-I., Papadopoulos, G., Gercken, B., Gebler, J., Schwabe, R. F., Chavakis, T., & Chatzigeorgiou, A. (2023). Analysis of the Role of Stellate Cell VCAM-1 in NASH Models in Mice. International Journal of Molecular Sciences, 24(5), 4813. https://doi.org/10.3390/ijms24054813
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Filliol, A., Saito, Y., Nair, A., Dapito, D. H., Yu, L.-X., Ravichandra, A., Bhattacharjee, S., Affo, S., Fujiwara, N., Su, H., Sun, Q., Savage, T. M., Wilson-Kanamori, J. R., Caviglia, J. M., Chin, L., Chen, D., Wang, X., Caruso, S., Kang, J. K., … Schwabe, R. F. (2022). Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis. Nature, 610(7931), 356–365. https://doi.org/10.1038/s41586-022-05289-6
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Choudhury, A., Ratna, A., Lim, A., Sebastian, R. M., Moore, C. L., Filliol, A. A., Bledsoe, J., Dai, C., Schwabe, R. F., Shoulders, M. D., & Mandrekar, P. (2022). Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. Hepatology Communications, 6(10), 2781–2797. https://doi.org/10.1002/hep4.2058
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Columbia Affiliation
Fondevila, M. F., Fernandez, U., Heras, V., Parracho, T., Gonzalez-Rellan, M. J., Novoa, E., Porteiro, B., Alonso, C., Mayo, R., da Silva Lima, N., Iglesias, C., Filliol, A. A., Senra, A., Delgado, T. C., Woodhoo, A., Herrero, L., Serra, D., Prevot, V., Schwaninger, M., … Nogueiras, R. (2022). Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis. Journal of Hepatology, 77(1), 15–28. https://doi.org/10.1016/j.jhep.2022.02.003
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Mederacke, I., Filliol, A., Affo, S., Nair, A., Hernandez, C., Sun, Q., Hamberger, F., Brundu, F., Chen, Y., Ravichandra, A., Huebener, P., Anke, H., Shi, H., Martínez García de la Torre, R. A., Smith, J. R., Henderson, N. C., Vondran, F. W. R., Rothlin, C. V., Baehre, H., … Schwabe, R. F. (2022). The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver. Science Translational Medicine, 14(639). https://doi.org/10.1126/scitranslmed.abe5795
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