Arachidonate 15-Lipoxygenase

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Samovich, S. N., Mikulska‐Ruminska, K., Dar, H. H., Tyurina, Y. Y., Tyurin, V. A., Souryavong, A. B., Kapralov, A. A., Amoscato, A. A., Beharier, O., Karumanchi, S. A., St Croix, C. M., Yang, X., Holman, T. R., VanDemark, A. P., Sadovsky, Y., Mallampalli, R. K., Wenzel, S. E., Gu, W., Bunimovich, Y. L., … Bayir, H. (2024). Strikingly High Activity of 15‐Lipoxygenase Towards Di‐Polyunsaturated Arachidonoyl/Adrenoyl‐Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death. Angewandte Chemie International Edition, 63(9). Portico. https://doi.org/10.1002/anie.202314710
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Manivarma, T., Kapralov, A. A., Samovich, S. N., Tyurina, Y. Y., Tyurin, V. A., VanDemark, A. P., Nowak, W., Bayır, H., Bahar, I., Kagan, V. E., & Mikulska-Ruminska, K. (2023). Membrane regulation of 15LOX-1/PEBP1 complex prompts the generation of ferroptotic signals, oxygenated PEs. Free Radical Biology and Medicine, 208, 458–467. https://doi.org/10.1016/j.freeradbiomed.2023.09.001
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