Factors Affecting Vaccine Hesitancy and Acceptance

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Bradford Bertumen, J., Benist, S., South, E., Ivy Oyegun, E., Smith-Jeffcoat, S. E., Grijalva, C. G., Zhu, Y., Scott, T. A., Schmitz, J., Chu, H. Y., Weil, A. A., Englund, J. A., MacMillan, M. P., Stockwell, M., McLaren, S. H., Sano, E., Vargas, C., Talbot, K., & Kirking, H. L. (2025). P-2071. 2023-2024 COVID-19 Vaccine Uptake, Knowledge, and Attitudes among Individuals enrolled in a Household Transmission Study, Tennessee, New York, and Washington, January-April 2024. Open Forum Infectious Diseases, 12(Supplement_1). https://doi.org/10.1093/ofid/ofae631.2227
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Rowley, E. A., Mitchell, P. K., Yang, D.-H., Lewis, N., Dixon, B. E., Vazquez-Benitez, G., Fadel, W. F., Essien, I. J., Naleway, A. L., Stenehjem, E., Ong, T. C., Gaglani, M., Natarajan, K., Embi, P., Wiegand, R. E., Link-Gelles, R., Tenforde, M. W., & Fireman, B. (2025). Methods to Adjust for Confounding in Test-Negative Design COVID-19 Effectiveness Studies: Simulation Study. JMIR Formative Research, 9, e58981. https://doi.org/10.2196/58981
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Heck, C. J., Kripke, K., Dam, A., Torres-Rueda, S., Bozzani, F., Obermeyer, C., Yohannes, K., Deacon, J., Meyers, K., Quigee, D., Wiant, S., Forsythe, S., Malati, C., Larson, M., Sobieszczyk, M. E., & Castor, D. (2024). Leveraging international stakeholders’ experiences with oral PrEP costs to accelerate implementation of the monthly dapivirine vaginal ring: A qualitative study. Health Research Policy and Systems, 22(1). https://doi.org/10.1186/s12961-024-01240-5
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Janes, H., Fisher, L. H., Kee, J. J., Parameswaran, L., Goepfert, P. A., Falsey, A. R., Ludwig, J., Magaret, C. A., Gilbert, P. B., Kublin, J. G., Rouphael, N., Sobieszczyk, M. E., El Sahly, H. M., Baden, L. R., Grinsztejn, B., Walsh, S. R., Gray, G. E., Kotloff, K. L., Gay, C. L., … Huang, Y. (2024). Association Between SARS-CoV-2 Viral Load and COVID-19 Vaccination in 4 Phase 3 Trials. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiae400
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Saad-Roy, C. M., Morris, S. E., Boots, M., Baker, R. E., Lewis, B. L., Farrar, J., Marathe, M. V., Graham, A. L., Levin, S. A., Wagner, C. E., Metcalf, C. J. E., & Grenfell, B. T. (2024). Impact of waning immunity against SARS-CoV-2 severity exacerbated by vaccine hesitancy. PLOS Computational Biology, 20(8), e1012211. https://doi.org/10.1371/journal.pcbi.1012211
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Bidari, S., & Yang, W. (2024). Global resurgence of measles in the vaccination era and influencing factors. International Journal of Infectious Diseases, 147, 107189. https://doi.org/10.1016/j.ijid.2024.107189
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Kogan, C. S., Stein, D. J., Garcia-Pacheco, J. A., Rebello, T. J., Montoya, M. I., Robles, R., Khoury, B., Kulygina, M., Matsumoto, C., Huang, J., Medina-Mora, M. E., Gureje, O., Sharan, P., Gaebel, W., Kanba, S., Andrews, H. F., Roberts, M. C., Pike, K. M., Zhao, M., … Reed, G. M. (2024). COVID-19 vaccine attitudes among mental health professionals in the WHO’s global clinical practice network. PLOS Mental Health, 1(1), e0000018. https://doi.org/10.1371/journal.pmen.0000018
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Kainth, M. K., Sembajwe, G. N., Ahn, H., Qian, M., Carrington, M., Armellino, D., & Jan, S. (2024). Despite mandated primary series, health care personnel still hesitant about COVID-19 vaccine and immunizing children. Vaccine, 42(12), 3122–3133. https://doi.org/10.1016/j.vaccine.2024.04.028
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Adams, K., Weber, Z. A., Yang, D.-H., Klein, N. P., DeSilva, M. B., Dascomb, K., Irving, S. A., Naleway, A. L., Rao, S., Gaglani, M., Flannery, B., Garg, S., Kharbanda, A. B., Grannis, S. J., Ong, T. C., Embi, P. J., Natarajan, K., Fireman, B., Zerbo, O., … Tenforde, M. W. (2023). Vaccine Effectiveness Against Pediatric Influenza-A–Associated Urgent Care, Emergency Department, and Hospital Encounters During the 2022–2023 Season: VISION Network. Clinical Infectious Diseases, 78(3), 746–755. https://doi.org/10.1093/cid/ciad704
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Levy, M. E., Yang, D., Dunne, M. M., Miley, K., Irving, S. A., Grannis, S. J., Weber, Z. A., Griggs, E. P., Spark, T. L., Bassett, E., Embi, P. J., Gaglani, M., Natarajan, K., Valvi, N. R., Ong, T. C., Naleway, A. L., Stenehjem, E., Klein, N. P., Link‐Gelles, R., … Ball, S. W. (2024). Risk of COVID‐19 Hospitalization and Protection Associated With mRNA Vaccination Among US Adults With Psychiatric Disorders. Influenza and Other Respiratory Viruses, 18(3). Portico. https://doi.org/10.1111/irv.13269
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Tenforde, M. W., Weber, Z. A., Yang, D.-H., DeSilva, M. B., Dascomb, K., Irving, S. A., Naleway, A. L., Gaglani, M., Fireman, B., Lewis, N., Zerbo, O., Goddard, K., Timbol, J., Hansen, J. R., Grisel, N., Arndorfer, J., McEvoy, C. E., Essien, I. J., Rao, S., … Klein, N. P. (2023). Influenza Vaccine Effectiveness Against Influenza A–Associated Emergency Department, Urgent Care, and Hospitalization Encounters Among US Adults, 2022–2023. The Journal of Infectious Diseases, 230(1), 141–151. https://doi.org/10.1093/infdis/jiad542
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Paintsil, E., Alimi, Y., Abdulaziz, M., Ogbuagu, O., Ogunsola, F., Kessy, S. J., Horsney, E., Lee, C., Brundney, K., Okwor, T., Kabwe, P., Waheed, A., Vondran, A., Bigirimana, R., Ilesanmi, O., Nsubuga, D. N., Raji, T., Mankoula, W., Ihekweazu, C., & Nkengasong, J. (2023). A continent-wide effort and solidarity at curbing COVID-19 pandemic: the Africa task force for novel coronavirus (AFTCOR) infection prevention and control technical working group’s experience. BMC Public Health, 23(1). https://doi.org/10.1186/s12889-023-15706-8
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Kukafka, R., Millery, M., Pan, S., Silverman, T. B., Zhang, T., McGuinness, J. E., Crew, K. D., & Aguirre, A. N. (2023). Cognitive and emotional factors related to COVID-19 among high-risk ethnically diverse adults at the onset of the New York City outbreak: A cross-sectional survey. Humanities and Social Sciences Communications, 10(1). https://doi.org/10.1057/s41599-023-01679-x
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Rolfes, M. A., Talbot, H. K., Grace Morrissey, K., Stockwell, M., Maldonado, Y. A., McLean, H., Lutrick, K., Bowman, N. M., Rao, S., Salvatore, P. P., Izurieta, H., Schmitz, J., Zhu, Y., Hart, K. W., Battan-Wraith, S., Merrill, L. S., McLaren, S. H., Sano, E., Sarnquist, C., … Grijalva, C. G. (2023). 2080. Reduced risk of SARS-CoV-2 infection among household contacts with hybrid immunity from recent COVID-19 vaccination and SARS-CoV-2 infection. Open Forum Infectious Diseases, 10(Supplement_2). https://doi.org/10.1093/ofid/ofad500.150
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Holodniy, M., Pei, Y., Stack, G., Wade, C. L., Agrawal, Y., Barasch, N., Baddoura, F., Carmen Frias-Kletecka, M., Stacey Klutts, J., & Wang-rodriguez, J. (2023). 2353. SARS-CoV-2 Variants among US Veterans after COVID-19 Bivalent Vaccine Administration. Open Forum Infectious Diseases, 10(Supplement_2). https://doi.org/10.1093/ofid/ofad500.1974
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Patel, P., Schrader, K. E., Rice, C. E., Rowley, E., Cree, R. A., DeSilva, M. B., Embi, P. J., Gaglani, M., Grannis, S. J., Ong, T. C., Stenehjem, E., Naleway, A. L., Ball, S., Natarajan, K., Klein, N. P., Adams, K., Kharbanda, A., Ray, C., Link-Gelles, R., & Tenforde, M. W. (2023). Effectiveness of the Original Monovalent Coronavirus Disease 2019 Vaccines in Preventing Emergency Department or Urgent Care Encounters and Hospitalizations Among Adults With Disabilities: VISION Network, June 2021-September 2022. Open Forum Infectious Diseases, 10(11). https://doi.org/10.1093/ofid/ofad474
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Embi, P. J., Levy, M. E., Patel, P., DeSilva, M. B., Gaglani, M., Dascomb, K., Dunne, M. M., Klein, N. P., Ong, T. C., Grannis, S. J., Natarajan, K., Yang, D.-H., Stenehjem, E., Zerbo, O., McEvoy, C., Rao, S., Thompson, M. G., Konatham, D., Irving, S. A., … Naleway, A. L. (2023). Effectiveness of COVID-19 vaccines at preventing emergency department or urgent care encounters and hospitalizations among immunocompromised adults: An observational study of real-world data across 10 US states from August-December 2021. Vaccine, 41(37), 5424–5434. https://doi.org/10.1016/j.vaccine.2023.05.038
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Adams, K., Riddles, J. J., Rowley, E. A. K., Grannis, S. J., Gaglani, M., Fireman, B., Hartmann, E., Naleway, A. L., Stenehjem, E., Hughes, A., Dalton, A. F., Natarajan, K., Dascomb, K., Raiyani, C., Irving, S. A., Sloan-Aagard, C., Kharbanda, A. B., DeSilva, M. B., Dixon, B. E., … Tenforde, M. W. (2023). Number needed to vaccinate with a COVID-19 booster to prevent a COVID-19-associated hospitalization during SARS-CoV-2 Omicron BA.1 variant predominance, December 2021–February 2022, VISION Network: a retrospective cohort study. The Lancet Regional Health - Americas, 23, 100530. https://doi.org/10.1016/j.lana.2023.100530
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Link-Gelles, R., Weber, Z. A., Reese, S. E., Payne, A. B., Gaglani, M., Adams, K., Kharbanda, A. B., Natarajan, K., DeSilva, M. B., Dascomb, K., Irving, S. A., Klein, N. P., Grannis, S. J., Ong, T. C., Embi, P. J., Dunne, M. M., Dickerson, M., McEvoy, C., Arndorfer, J., … Tenforde, M. W. (2023). Estimates of Bivalent mRNA Vaccine Durability in Preventing COVID-19–Associated Hospitalization and Critical Illness Among Adults with and Without Immunocompromising Conditions — VISION Network, September 2022–April 2023. American Journal of Transplantation, 23(7), 1062–1076. https://doi.org/10.1016/j.ajt.2023.06.004
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Schnall, R., Ramirez, S. O., Padilla, J. J., Halpern, M., Olender, S., & Baez, P. (2023). Expert Feedback on the Adaptation and Translation of Spanish Version of WiseApp. Caring Is Sharing – Exploiting the Value in Data for Health and Innovation. https://doi.org/10.3233/shti230190
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Dalton, A. F., Weber, Z. A., Allen, K. S., Stenehjem, E., Irving, S. A., Spark, T. L., Adams, K., Zerbo, O., Lazariu, V., Dixon, B. E., Dascomb, K., Hartmann, E., Kharbanda, A. B., Ong, T. C., DeSilva, M. B., Beaton, M., Gaglani, M., Patel, P., Naleway, A. L., … Tenforde, M. W. (2023). Relationships Between Social Vulnerability and Coronavirus Disease 2019 Vaccination Coverage and Vaccine Effectiveness. Clinical Infectious Diseases, 76(9), 1615–1625. https://doi.org/10.1093/cid/ciad003
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Dawood, F. S., Couture, A., Zhang, X., Stockwell, M. S., Porucznik, C. A., Stanford, J. B., Hetrich, M., Veguilla, V., Thornburg, N., Heaney, C. D., Wang, J., Duque, J., Jeddy, Z., Deloria Knoll, M., & Karron, R. (2023). Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibody Responses After Community Infections in Children and Adults. Open Forum Infectious Diseases, 10(5). https://doi.org/10.1093/ofid/ofad168
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DeSilva, M. B., Mitchell, P. K., Klein, N. P., Dixon, B. E., Tenforde, M. W., Thompson, M. G., Naleway, A. L., Grannis, S. J., Ong, T. C., Natarajan, K., Reese, S. E., Zerbo, O., Kharbanda, A. B., Patel, P., Stenehjem, E., Raiyani, C., Irving, S. A., Fadel, W. F., Rao, S., … Gaglani, M. (2022). Protection of Two and Three mRNA Vaccine Doses Against Severe Outcomes Among Adults Hospitalized With COVID-19—VISION Network, August 2021 to March 2022. The Journal of Infectious Diseases, 227(8), 961–969. https://doi.org/10.1093/infdis/jiac458
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Harris, J. N., Mauro, C., Andresen, J. A., Zimet, G. D., & Rosenthal, S. L. (2022). COVID-19 vaccine uptake and attitudes towards mandates in a nationally representative U.S. sample. Journal of Behavioral Medicine, 46(1–2), 25–39. https://doi.org/10.1007/s10865-022-00317-2
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Link-Gelles, R., Levy, M. E., Natarajan, K., Reese, S. E., Naleway, A. L., Grannis, S. J., Klein, N. P., DeSilva, M. B., Ong, T. C., Gaglani, M., Hartmann, E., Dickerson, M., Stenehjem, E., Kharbanda, A. B., Han, J., Spark, T. L., Irving, S. A., Dixon, B. E., Zerbo, O., … Tenforde, M. W. (2023). Estimation of COVID-19 mRNA Vaccine Effectiveness and COVID-19 Illness and Severity by Vaccination Status During Omicron BA.4 and BA.5 Sublineage Periods. JAMA Network Open, 6(3), e232598. https://doi.org/10.1001/jamanetworkopen.2023.2598
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Tarun, S., Abebe, W., Mahida, M., Saiman, L., James, W., LaRussa, P., & Stanberry, L. R. (2023). Diagnosis, Treatment, and Prevention Resources for Infectious Diseases in Sub-Saharan African Hospitals Caring for Children. Global Pediatric Health, 10. https://doi.org/10.1177/2333794x231210661
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Stockwell, M. S., Porucznik, C. A., Dixon, A., Duque, J., Stanford, J. B., Veguilla, V., & Dawood, F. S. (2022). Factors Associated with Intention to Vaccinate Children 0-11 Years of Age Against COVID-19. The Journal of the American Board of Family Medicine, 35(6), 1174–1178. https://doi.org/10.3122/jabfm.2022.220150r1
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Guzman, C. P., Aron, J., Egbebike, J., Greene, M. C., Reisig, C., DeFilippo, M., Bollman, E. B., Stefan, B. R., Chang, B. P., Wagh, A., & Firew, T. (2022). COVID‐19 vaccine controversy: A cross‐sectional analysis of factors associated with COVID‐19 vaccine acceptance amongst emergency department patients in New York City. Journal of the American College of Emergency Physicians Open, 3(6). Portico. https://doi.org/10.1002/emp2.12830
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Ferdinands, J. M., Rao, S., Dixon, B. E., Mitchell, P. K., DeSilva, M. B., Irving, S. A., Lewis, N., Natarajan, K., Stenehjem, E., Grannis, S. J., Han, J., McEvoy, C., Ong, T. C., Naleway, A. L., Reese, S. E., Embi, P. J., Dascomb, K., Klein, N. P., Griggs, E. P., … Fireman, B. (2022). Waning of vaccine effectiveness against moderate and severe covid-19 among adults in the US from the VISION network: test negative, case-control study. BMJ, e072141. https://doi.org/10.1136/bmj-2022-072141
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Mergenova, G., Rosenthal, S., Zhussupov, B., Izekenova, A., Alekesheva, L., Izekenova, A., Iskakova, B., Myrkassymova, A., Bukharbayeva, A., & Davis, A. (2022). COVID-19 vaccination hesitancy in Kazakhstan. European Journal of Public Health, 32(Supplement_3). https://doi.org/10.1093/eurpub/ckac129.662
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Andresen, J. A., Harris, J. N., Mauro, C., Zimet, G. D., & Rosenthal, S. L. (2022). The impact of financial incentives on COVID-19 vaccination intention among a sample of U.S. adults. Preventive Medicine Reports, 29, 101962. https://doi.org/10.1016/j.pmedr.2022.101962
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Sobieszczyk, M. E., Maaske, J., Falsey, A. R., Sproule, S., Robb, M. L., Frenck, R. W., Tieu, H.-V., Mayer, K. H., Corey, L., Neuzil, K. M., Tong, T., Brewinski Isaacs, M., Janes, H., Bansal, H., Edwards, L. M., Green, J. A., Kelly, E. J., Shoemaker, K., Takas, T., … Hirsch, and I. (2022). Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months. Journal of Clinical Investigation, 132(18). https://doi.org/10.1172/jci160565
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Ostropolets, A., & Hripcsak, G. (2022). COVID-19 vaccination effectiveness rates by week and sources of bias: a retrospective cohort study. BMJ Open, 12(8), e061126. https://doi.org/10.1136/bmjopen-2022-061126
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Low, A., Wright, C., Platt, J., Chang, C., Mantell, J. E., Romero, E., Hoos, D., Mannheimer, S., Greenleaf, A., Castor, D., & El-Sadr, W. M. (2022). COVID-19 Vaccine Uptake and Factors Associated With Being Unvaccinated Among Lesbian, Gay, Bisexual, Transgender, Queer, and Other Sexual Identities (LGBTQ+) New Yorkers. Open Forum Infectious Diseases, 9(7). https://doi.org/10.1093/ofid/ofac260
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Diaz, D., Chacko, S., Sperling, A., Fleck, E., Louh, I., Trepp, R., & Ye, S. (2022). Assessment of Digital and Community-Based Outreach Interventions to Encourage COVID-19 Vaccination Uptake in an Underserved Community. JAMA Network Open, 5(6), e2217875. https://doi.org/10.1001/jamanetworkopen.2022.17875
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Ostropolets, A., Ryan, P. B., Schuemie, M. J., & Hripcsak, G. (2022). Characterizing Anchoring Bias in Vaccine Comparator Selection Due to Health Care Utilization With COVID-19 and Influenza: Observational Cohort Study. JMIR Public Health and Surveillance, 8(6), e33099. https://doi.org/10.2196/33099
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Ostropolets, A., Li, X., Makadia, R., Rao, G., Rijnbeek, P. R., Duarte-Salles, T., Sena, A. G., Shaoibi, A., Suchard, M. A., Ryan, P. B., Prieto-Alhambra, D., & Hripcsak, G. (2022). Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.814198
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