Inhibition of Abl Kinase by Imatinib Can Rescue the Compromised Barrier Function of 22q11.2DS Patient-iPSC-Derived Blood–Brain Barriers

Li, Y., Sun, Z., Zhu, H., Sun, Y., Shteyman, D. B., Markx, S., Leong, K. W., Xu, B., & Fu, B. M. (2023). Inhibition of Abl Kinase by Imatinib Can Rescue the Compromised Barrier Function of 22q11.2DS Patient-iPSC-Derived Blood–Brain Barriers. Cells, 12(3), 422. https://doi.org/10.3390/cells12030422
Authors:
Yunfei Li
Zhixiong Sun
Huixiang Zhu
Yan Sun
David B. Shteyman
Sander Markx
Kam W. Leong
Bin Xu
Bingmei M. Fu
Affiliated Authors:
Zhixiong Sun
Huixiang Zhu
Yan Sun
Sander Markx
Kam W. Leong
Bin Xu
Columbia Affiliation:
Author Keywords:
abl/crkl signaling pathway
blood–brain barrier
digeorge syndrome
endothelial glycocalyx
imatinib
permeability
tight junction
transcription network
elink
Publication Type:
Article
Unique ID:
10.3390/cells12030422
PMID:
36766762
DOI:
10.3390/cells12030422
Journal:
Cells
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

Record Created: