Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma

Yoon, A. J., Carvajal, R. D., Graboyes, E. M., Kaczmar, J. M., Albergotti, W. G., Kejner, A. E., Troob, S. H., Philipone, E., Anoma, J.-S., Armeson, K. E., Hill, E. G., Richardson, M. S., Woods, T. R., Chera, B. S., Nourollah-Zadeh, F., Lee, B. J., Pandruvada, S., Kourtidis, A., Kingsley, C., … Newman, J. G. (2025). Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma. Frontiers in Immunology, 16. https://doi.org/10.3389/fimmu.2025.1530262
Authors:
Angela J. Yoon
Richard D. Carvajal
Evan M. Graboyes
John M. Kaczmar
William G. Albergotti
Alexandra E. Kejner
Scott H. Troob
Elizabeth Philipone
Jean-Sebastien Anoma
Kent Armeson
Elizabeth G. Hill
Mary S. Richardson
Tina R. Woods
Bhishamjit S. Chera
Farzad Nourollah-Zadeh
Byung Ju Lee
Subramanya Pandruvada
Antonis Kourtidis
Christina Kingsley
Elizabeth C. O’Quinn
Stephanie Mills
V. Craig Jordan
M. Spencer
Danielle Fails
Trevor D. McKee
Mark Zaidi
Alan Brisendine
Sarah Horn
Shikhar Mehrotra
Besim Öğretmen
Jason G. Newman
Affiliated Authors:
Scott H. Troob
Elizabeth Philipone
Columbia Affiliation:
Subjects:
Imiquimod (MeSH)
Toll-Like Receptor 7 (MeSH)
Mouth Neoplasms (MeSH)
Immunotherapy (MeSH)
Neoadjuvant Therapy (MeSH)
Epidemiology and Treatment of Head and Neck Cancer (OpenAlex Topic)
Cancer Immunotherapy (OpenAlex Topic)
Immunobiology of Dendritic Cells (OpenAlex Topic)
Author Keywords:
oral cancer
neoadjuvant clinical trial
toll-like 7 receptor agonist
imiquimod
immunotherapy
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Publication Type:
Article
Unique ID:
10.3389/fimmu.2025.1530262
PMID:
39931064
DOI:
10.3389/fimmu.2025.1530262
Journal:
Frontiers in Immunology
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: