Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq

Zhao, W., Dovas, A., Spinazzi, E. F., Levitin, H. M., Banu, M. A., Upadhyayula, P., Sudhakar, T., Marie, T., Otten, M. L., Sisti, M. B., Bruce, J. N., Canoll, P., & Sims, P. A. (2021). Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq. Genome Medicine, 13(1). https://doi.org/10.1186/s13073-021-00894-y
Authors:
Wenting Zhao
Athanassios Dovas
Eleonora Francesca Spinazzi
Hanna Mendes Levitin
Matei Alexandru Banu
Pavan Upadhyayula
Tejaswi Sudhakar
Tamara Marie
Marc L. Otten
Michael B. Sisti
Jeffrey N. Bruce
Peter Canoll
Peter A. Sims
Affiliated Authors:
Wenting Zhao
Athanassios Dovas
Eleonora Francesca Spinazzi
Hanna Mendes Levitin
Matei Alexandru Banu
Pavan Upadhyayula
Tejaswi Sudhakar
Tamara Marie
Marc L. Otten
Michael B. Sisti
Jeffrey N. Bruce
Peter Canoll
Peter A. Sims
Columbia Affiliation:
Author Keywords:
drug perturbation
etoposide
glioblastoma
panobinostat
single-cell rna sequencing (scrna-seq)
tissue slice culture
tumor heterogeneity
tumor microenvironment
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Publication Type:
Article
Unique ID:
10.1186/s13073-021-00894-y
PMID:
33975634
DOI:
10.1186/s13073-021-00894-y
Journal:
Genome Medicine
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record

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