Obesity-related IL-18 impairs T-regulatory cell function and promotes lung ischemia–reperfusion injury

Akimova, T., Zhang, T., Christensen, L. M., Wang, Z., Han, R., Negorev, D., Samanta, A., Sasson, I. E., Gaddapara, T., Jiao, J., Wang, L., Bhatti, T. R., Levine, M. H., Diamond, J. M., Beier, U. H., Simmons, R. A., Cantu, E., Wilkes, D. S., Lederer, D. J., … Hancock, W. W. (2021). Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia–Reperfusion Injury. American Journal of Respiratory and Critical Care Medicine, 204(9), 1060–1074. https://doi.org/10.1164/rccm.202012-4306oc
Authors:
Tatiana Akimova
Tianyi Zhang
Lanette M. Christensen
Zhonglin Wang
Rongxiang Han
Dmitry Negorev
Arabinda Samanta
Isaac E. Sasson
Trivikram Gaddapara
Jing Jiao
Liqing Wang
Tricia R. Bhatti
Matthew H. Levine
Joshua M. Diamond
Ulf H. Beier
Rebecca A. Simmons
Edward Cantu
David S. Wilkes
David J. Lederer
Michaela Anderson
Jason D. Christie
Wayne W. Hancock
Affiliated Authors:
David J. Lederer
Michaela Anderson
Columbia Affiliation:
Subjects:
Acute Lung Injury (MeSH)
Interleukin-18 (MeSH)
Lung Transplantation (MeSH)
Obesity (MeSH)
Primary Graft Dysfunction (MeSH)
Reperfusion Injury (MeSH)
T-Lymphocytes, Regulatory (MeSH)
Author Keywords:
il-18
lung transplant
obesity
primary graft dysfunction
regulatory t cells
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Publication Type:
Article
Unique ID:
10.1164/rccm.202012-4306OC
PMID:
34346860
DOI:
10.1164/rccm.202012-4306OC
Journal:
American Journal of Respiratory and Critical Care Medicine
Publication Date:
Data Source:
Scopus
Source Link:
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Record Created: