Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target

Arai, J., Hayakawa, Y., Tateno, H., Murakami, K., Hayashi, T., Hata, M., Matsushita, Y., Kinoshita, H., Abe, S., Kurokawa, K., Oya, Y., Tsuboi, M., Ihara, S., Niikura, R., Suzuki, N., Iwata, Y., Shiokawa, T., Shiomi, C., Uekura, C., … Fujishiro, M. (2024). Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target. Gastroenterology, 167(3), 505-521.e19. https://doi.org/10.1053/j.gastro.2024.03.037
Authors:
Junya Arai
Yoku Hayakawa
Hiroaki Tateno
Keita Murakami
Takeru Hayashi
Masahiro Hata
Yuki Matsushita
Hiroto Kinoshita
Sohei Abe
Ken Kurokawa
Yukiko Oya
Mayo Tsuboi
Sozaburo Ihara
Ryota Niikura
Nobumi Suzuki
Yusuke Iwata
Toshiro Shiokawa
Chihiro Shiomi
Chie Uekura
Keisuke Yamamoto
Hiroaki Fujiwara
Satoshi Kawamura
Hayato Nakagawa
Seiya Mizuno
Takashi Kudo
Satoru Takahashi
Tetsuo Ushiku
Yoshihiro Hirata
Chifumi Fujii
Jun Nakayama
Shinsuke Shibata
Susan Woods
Daniel L Worthley
Masanori Hatakeyama
Timothy C Wang
Mitsuhiro Fujishiro
Affiliated Authors:
Timothy C Wang
Columbia Affiliation:
Subjects:
Stomach Neoplasms (MeSH)
Mucin-6 (MeSH)
Mice, Knockout (MeSH)
Author Keywords:
muc6
golph3
golgi stress
gastric cancer
mapk pathway
elink
Publication Type:
Article
Unique ID:
10.1053/j.gastro.2024.03.037
PMID:
38583723
DOI:
10.1053/j.gastro.2024.03.037
Journal:
Gastroenterology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record

Record Created: