Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis

Rajeswaran, W., Ashkar, S. R., Lee, P. H., Yeomans, L., Shin, Y., Franzblau, S. G., Murakami, K. S., Showalter, H. D., & Garcia, G. A. (2022). Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. ACS Infectious Diseases, 8(8), 1422–1438. https://doi.org/10.1021/acsinfecdis.1c00636
Authors:
Walajapet Rajeswaran
Pil H. Lee
Shireen R. Ashkar
Larisa Yeomans
Hollis D. Showalter
George A. Garcia
Yeonoh Shin
Katsuhiko S. Murakami
Scott G. Franzblau
Affiliated Authors:
Yeonoh Shin
Columbia Affiliation:
Author Keywords:
rifamycin
benzoxazinorifamycin
rna polymerase
drug-drug interactions
adverse drug effects
mouse efficacy
elink
Publication Type:
Article
Unique ID:
10.1021/acsinfecdis.1c00636
PMID:
35772744
DOI:
10.1021/acsinfecdis.1c00636
Journal:
ACS Infectious Diseases
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record

Record Created: