Anti-PD1 prolongs the response of PI3K and farnesyl transferase inhibition in HRAS- and PIK3CA-mutant head and neck cancers

Manikandan, D. B., Jagadeeshan, S., Mathukkada, S., Shareb, R. A., Prasad, M., Belsamma, L. V. S., Marripati, D., Erez, N., Wainer, M., Geva, A., Raviv, D., Allon, I., Morris, L. G., Su, G. H., Wang, H., Rosenberg, A. J., Kessler, L., Burrows, F., & Elkabets, M. (2025). Anti-PD1 prolongs the response of PI3K and farnesyl transferase inhibition in HRAS- and PIK3CA-mutant head and neck cancers. Neoplasia, 63, 101157. https://doi.org/10.1016/j.neo.2025.101157
Authors:
Dinesh Babu Manikandan
Sankar Jagadeeshan
Sooraj Mathukkada
Raghda Abu Shareb
Manu Prasad
Liju Vijaya Steltar Belsamma
Divyasree Marripati
Noga Erez
Monica Wainer
Amit Geva
Danielle Raviv
Irit Allon
Luc Gt Morris
Gloria H Su
Hai Wang
Ari J Rosenberg
Linda Kessler
Francis Burrows
Moshe Elkabets
Affiliated Authors:
Gloria H Su
Author Keywords:
alpelisib
anti-pd1
hras
head and neck cancer
pi3k
tipifarnib
Publication Type:
Article
Unique ID:
10.1016/j.neo.2025.101157
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created: