Prostaglandin E2 and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer

Good, H. J., Larsen, F., Shin, A. E., Zhang, L., Derouet, M., Meriwether, D., Worthley, D., Reddy, S. T., Wang, T. C., & Asfaha, S. (2025). Prostaglandin E2 and Akt promote stemness in Apc mutant Dclk1+ cells to give rise to colitis-associated cancer. Cellular and Molecular Gastroenterology and Hepatology, 101469. https://doi.org/10.1016/j.jcmgh.2025.101469
Authors:
Hayley J Good
Frederikke Larsen
Alice E Shin
Liyue Zhang
Mathieu Derouet
David Meriwether
Daniel Worthley
Srinivasa T Reddy
Timothy C Wang
Samuel Asfaha
Affiliated Authors:
Timothy C Wang
Author Keywords:
aspirin
colitis
colon cancer
dclk1
stem cells
Publication Type:
Article
Unique ID:
10.1016/j.jcmgh.2025.101469
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created: