A variant of the Hspa8 synaptic chaperone modifies disease in a SOD1G86R mouse model of amyotrophic lateral sclerosis

Takeda, T., Her, Y.-R., Kim, J.-K., Jha, N. N., & Monani, U. R. (2025). A variant of the Hspa8 synaptic chaperone modifies disease in a SOD1G86R mouse model of amyotrophic lateral sclerosis. Experimental Neurology, 383, 115024. https://doi.org/10.1016/j.expneurol.2024.115024
Authors:
Taishi Takeda
Yoon-Ra Her
Jeong-Ki Kim
Narendra N Jha
Umrao R Monani
Affiliated Authors:
Taishi Takeda
Yoon-Ra Her
Jeong-Ki Kim
Narendra N Jha
Umrao R Monani
Columbia Affiliation:
Subjects:
Amyotrophic Lateral Sclerosis (MeSH)
Disease Models, Animal (MeSH)
Mice, Transgenic (MeSH)
HSC70 Heat-Shock Proteins (MeSH)
Superoxide Dismutase-1 (MeSH)
Author Keywords:
amyotrophic lateral sclerosis
hspa8
modifier
mouse models
sod1
spinal muscular atrophy
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Publication Type:
Article
Unique ID:
10.1016/j.expneurol.2024.115024
PMID:
39454934
DOI:
10.1016/j.expneurol.2024.115024
Journal:
Experimental Neurology
Publication Date:
Data Source:
PubMed
Source Link:
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