Inavolisib plus letrozole or fulvestrant in PIK3CA-mutated, hormone receptor-positive, HER2-negative advanced or metastatic breast cancer (GO39374): An open-label, multicentre, dose-escalation and dose-expansion phase 1/1b study

Bedard, P. L., Jhaveri, K. L., Accordino, M. K., Cervantes, P. A., Gambardella, V., Hamilton, E., Italiano, P. A., Kalinsky, P. K., Krop, P. I. E., Oliveira, M., Schmid, P. P., Saura, C., Turner, P. N., Varga, A., Cheeti, S., Dey, A., Hilz, S., Hutchinson, K. E., Jin, Y., … Juric, D. (2025). Inavolisib plus letrozole or fulvestrant in PIK3CA-mutated, hormone receptor-positive, HER2-negative advanced or metastatic breast cancer (GO39374): An open-label, multicentre, dose-escalation and dose-expansion phase 1/1b study. European Journal of Cancer, 221, 115397. https://doi.org/10.1016/j.ejca.2025.115397
Authors:
Philippe L Bedard
Komal L Jhaveri
Melissa K Accordino
Prof Andrés Cervantes
Valentina Gambardella
Erika Hamilton
Prof Antoine Italiano
Prof Kevin Kalinsky
Prof Ian E Krop
Mafalda Oliveira
Prof Peter Schmid
Cristina Saura
Prof Nicholas Turner
Andrea Varga
Sravanthi Cheeti
Anwesha Dey
Stephanie Hilz
Katherine E Hutchinson
Yanling Jin
Stephanie Royer-Joo
Ubong Peters
Noopur Shankar
Jennifer L Schutzman
Junko Aimi
Kyung Song
Dejan Juric
Affiliated Authors:
Melissa K Accordino
Prof Kevin Kalinsky
Author Keywords:
breast
fulvestrant
letrozole
metastatic
phase i
Publication Type:
Article
Unique ID:
10.1016/j.ejca.2025.115397
PMID:
Publication Date:
Data Source:
PubMed

Record Created: