4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease

Corral-Sarasa, J., Martínez-Gálvez, J. M., González-García, P., Wendling, O., Jiménez-Sánchez, L., López-Herrador, S., Quinzii, C. M., Díaz-Casado, M. E., & López, L. C. (2024). 4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease. Cell Reports, 43(5), 114148. https://doi.org/10.1016/j.celrep.2024.114148
Authors:
Julia Corral-Sarasa
Juan Manuel Martinez Galvez
Pilar González-García
Olivia Wendling
Laura Jiménez-Sánchez
Sergio López-Herrador
Catarina M. Quinzii
María E. Diaz‐Casado
Luís C. López
Affiliated Authors:
Catarina M. Quinzii
Columbia Affiliation:
Subjects:
Mitochondrial Diseases (MeSH)
Parabens (MeSH)
Disease Models, Animal (MeSH)
Ubiquinone (MeSH)
Metabolism and Functions of Coenzyme Q (OpenAlex Topic)
Mitochondrial Dynamics and Reactive Oxygen Species Regulation (OpenAlex Topic)
Role of Lipoic Acid in Metabolism and Health (OpenAlex Topic)
Author Keywords:
4-hydroxybenzoic acid
cardiac insufficiency
coenzyme q deficiency
coq biosynthesis
cp: metabolism
metabolic disorders
mitochondrial diseases
neurodevelopmental disorders
perinatal lethality
pharmacological therapy
translational medicine
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Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.114148
PMID:
38697100
DOI:
10.1016/j.celrep.2024.114148
Journal:
Cell Reports
Publication Date:
Data Source:
OpenAlex
Source Link:
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