Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration

Dermentzaki, G., Furlan, M., Tanaka, I., Leonardi, T., Rinchetti, P., Passos, P. M. S., Bastos, A., Ayala, Y. M., Hanna, J. H., Przedborski, S., Bonanomi, D., Pelizzola, M., & Lotti, F. (2024). Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration. Cell Reports, 43(4), 113999. https://doi.org/10.1016/j.celrep.2024.113999
Authors:
Georgia Dermentzaki
Mattia Furlan
Iris Tanaka
Tommaso Leonardi
Paola Rinchetti
Patricia M S Passos
Alliny Bastos
Yuna M Ayala
Jacob H Hanna
Serge Przedborski
Dario Bonanomi
Mattia Pelizzola
Francesco Lotti
Affiliated Authors:
Georgia Dermentzaki
Paola Rinchetti
Serge Przedborski
Francesco Lotti
Columbia Affiliation:
Subjects:
Cholinergic Neurons (MeSH)
Methyltransferases (MeSH)
Neuromuscular Diseases (MeSH)
Author Keywords:
als
cp: neuroscience
ftd
mettl3
n6-methyladenosine
rna epigenetics
rna metabolism
tdp-43
age-related neurodegeneration
amyotrophic lateral sclerosis
frontotemporal dementia
m6a
methyltransferase-like 3
motor neurons
transactive response dna-binding protein-43
elink
Publication Type:
Article
Unique ID:
10.1016/j.celrep.2024.113999
PMID:
38554281
DOI:
10.1016/j.celrep.2024.113999
Journal:
Cell Reports
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record

Record Created: