525P Efficacy, safety, pharmacokinetic (PK) and pharmacodynamic (PD) data from phase I dose escalation of a novel therapeutic peptide, ST101, targeting the oncogenic transcription factor C/EBPβ, in patients (pts) with advanced and metastatic solid tumors

Mckean, M. A., Lakhani, N. J., Arkenau, H.-T., Symeonides, S., Evans, T. R. J., Lim, E. A., Fontana, E., Bupathi, M., Mclaren, A., Chandana, S. R., Ding, T.-E., Rotolo, J., Capiaux, G., Michel, R., Kaesshaefer, S., Bexon, A., & Falchook, G. S. (2021). 525P Efficacy, safety, pharmacokinetic (PK) and pharmacodynamic (PD) data from phase I dose escalation of a novel therapeutic peptide, ST101, targeting the oncogenic transcription factor C/EBPβ, in patients (pts) with advanced and metastatic solid tumors. Annals of Oncology, 32, S592. https://doi.org/10.1016/j.annonc.2021.08.1047
Authors:
Meredith McKean
Nehal J. Lakhani
H-T. Arkenau
Stefan N. Symeonides
T.R. Jeffry Evans
Emerson A. Lim
Elisa Fontana
Manojkumar Bupathi
Alistair S. McLaren
Sree R Chandana
T-E. Ding
Jimmy A. Rotolo
Gina Capiaux
Robert G. Michel
Stephen Kaesshaefer
Alice Bexon
Gerald S. Falchook
Affiliated Authors:
Emerson A. Lim
Columbia Affiliation:
Subjects:
Mechanisms of Estrogen Receptor Signaling (OpenAlex Topic)
Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer (OpenAlex Topic)
Cancer Stem Cells and Tumor Metastasis (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1016/j.annonc.2021.08.1047
DOI:
10.1016/j.annonc.2021.08.1047
Journal:
Annals of Oncology
Publication Date:
Data Source:
OpenAlex
Source Link:
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