Microneedle-mediated intracochlear injection safely achieves higher perilymphatic dexamethasone concentration than intratympanic delivery in guinea pig

Voruz, F., Feng, S. J., Breil, E., Yu, M., Hammer, D. R., Aksit, A., Zandkarimi, F., Olson, E. S., Kysar, J. W., & Lalwani, A. K. (2025). Microneedle-mediated intracochlear injection safely achieves higher perilymphatic dexamethasone concentration than intratympanic delivery in guinea pig. Drug Delivery and Translational Research. https://doi.org/10.1007/s13346-025-01821-z
Authors:
François Voruz
Sharon J Feng
Eugénie Breil
Michelle Yu
Daniella R Hammer
Aykut Aksit
Fereshteh Zandkarimi
Elizabeth S Olson
Jeffrey W Kysar
Anil K Lalwani
Affiliated Authors:
François Voruz
Sharon J Feng
Eugénie Breil
Michelle Yu
Elizabeth S Olson
Jeffrey W Kysar
Anil K Lalwani
Columbia Affiliation:
Author Keywords:
corticosteroid
dexamethasone
hearing
inner ear drug delivery
microneedle
round window membrane
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Publication Type:
Article
Unique ID:
10.1007/s13346-025-01821-z
PMID:
40009130
DOI:
10.1007/s13346-025-01821-z
Journal:
Drug Delivery and Translational Research
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: