Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease

Dron, J. S., Patel, A. P., Zhang, Y., Jurgens, S. J., Maamari, D. J., Wang, M., Boerwinkle, E., Morrison, A. C., de Vries, P. S., Fornage, M., Hou, L., Lloyd-Jones, D. M., Psaty, B. M., Tracy, R. P., Bis, J. C., Vasan, R. S., Levy, D., Heard-Costa, N., Rich, S. S., … Khera, A. V. (2023). Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease. JAMA Cardiology, 8(3), 258. https://doi.org/10.1001/jamacardio.2022.5271
Authors:
Jacqueline S Dron
Aniruddh P Patel
Yiyi Zhang
Sean J Jurgens
Dimitri J Maamari
Minxian Wang
Eric Boerwinkle
Alanna C Morrison
Paul S de Vries
Myriam Fornage
Lifang Hou
Donald M Lloyd-Jones
Bruce M Psaty
Russell P Tracy
Joshua C Bis
Ramachandran S Vasan
Daniel Levy
Nancy Heard-Costa
Stephen S Rich
Xiuqing Guo
Kent D Taylor
Richard A Gibbs
Jerome I Rotter
Cristen J Willer
Elizabeth C Oelsner
Andrew E Moran
Gina M Peloso
Pradeep Natarajan
Amit V Khera
Affiliated Authors:
Yiyi Zhang
Elizabeth C Oelsner
Andrew E Moran
Columbia Affiliation:
Subjects:
Coronary Disease (MeSH)
Proprotein Convertase 9 (MeSH)
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Publication Type:
Article
Unique ID:
10.1001/jamacardio.2022.5271
PMID:
36723951
DOI:
10.1001/jamacardio.2022.5271
Journal:
JAMA Cardiology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: