Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial

Paganoni, S., Fournier, C. N., Macklin, E. A., Chibnik, L. B., Quintana, M., Saville, B. R., Detry, M. A., Vestrucci, M., Marion, J., McGlothlin, A., Ajroud-Driss, S., Chase, M., Pothier, L., Harkey, B. A., Yu, H., Sherman, A. V., Shefner, J. M., Hall, M., Kittle, G., … Torti, M. (2025). Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis. JAMA Network Open, 8(2), e2459058. https://doi.org/10.1001/jamanetworkopen.2024.59058
Authors:
Sabrina Paganoni
Christina N Fournier
Eric A Macklin
Lori B Chibnik
Melanie Quintana
Benjamin R Saville
Michelle A Detry
Matteo Vestrucci
Joe Marion
Anna McGlothlin
Senda Ajroud-Driss
Marianne Chase
Lindsay Pothier
Brittney A Harkey
Hong Yu
Alexander V Sherman
Jeremy M Shefner
Meghan Hall
Gale Kittle
James D Berry
Suma Babu
Jinsy Andrews
Derek Dagostino
Eric Tustison
Elisa Giacomelli
Erica Scirocco
Gustavo Alameda
Eduardo Locatelli
Doreen Ho
Adam Quick
Jonathan Katz
Daragh Heitzman
Stanley H Appel
Sheetal Shroff
Kevin Felice
Nicholas J Maragakis
Zachary Simmons
Timothy M Miller
Nicholas Olney
Michael D Weiss
Stephen A Goutman
Joseph Americo Fernandes
Omar Jawdat
Margaret Ayo Owegi
Laura A Foster
Tuan Vu
Hristelina Ilieva
Daniel S Newman
Ximena Arcila-Londono
Carlayne E Jackson
Shafeeq Ladha
Terry Heiman-Patterson
James B Caress
Andrea Swenson
Amanda Peltier
Richard Lewis
Dominic Fee
Matthew Elliott
Richard Bedlack
Edward J Kasarskis
Lauren Elman
Jeffrey Rosenfeld
David Walk
Courtney McIlduff
Paul Twydell
Eufrosina Young
Kristin Johnson
Kourosh Rezania
Namita A Goyal
Jeffrey A Cohen
Michael Benatar
Vovanti Jones
Jonathan Glass
Jaimin Shah
Said R Beydoun
James P Wymer
Lindsay Zilliox
Shakti Nayar
Gary L Pattee
Jennifer Martinez-Thompson
Brittany Harvey
Shital Patel
Paul Mahoney
Petra W Duda
Merit E Cudkowicz
Affiliated Authors:
Jinsy Andrews
Columbia Affiliation:
Subjects:
Amyotrophic Lateral Sclerosis (MeSH)
elink
Publication Type:
Article
Unique ID:
10.1001/jamanetworkopen.2024.59058
PMID:
39960672
DOI:
10.1001/jamanetworkopen.2024.59058
Journal:
JAMA Network Open
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Web of Science Record

Record Created: