Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification

Nguyen, T. B., Miramontes, R., Chillon-Marinas, C., Maimon, R., Vazquez-Sanchez, S., Lau, A. L., McClure, N. R., Wu, Z., Wang, K. Q., England, W. E., Singha, M., Stocksdale, J. T., Heath, M., Jang, K.-H., Jung, S., Ling, K., Jafar-nejad, P., McKnight, J. I., Ho, L. N., … Thompson, L. M. (2025). Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification. Nature Neuroscience, 28(2), 280–292. https://doi.org/10.1038/s41593-024-01850-w
Authors:
Thai B. Nguyen
Keona Q. Wang
Jennifer T. Stocksdale
Marie Heath
Leanne N. Ho
Leslie M. Thompson
Ricardo Miramontes
Jack C. Reidling
Carlos Chillon-Marinas
Roy Maimon
Sonia Vazquez-Sanchez
Don W. Cleveland
Alice L. Lau
Joan S. Steffan
Zhuoxing Wu
Sunhee Jung
Cholsoon Jang
Whitney E. England
Monika Singha
Robert C. Spitale
Ki-Hong Jang
Gina Lee
Karen Ling
Paymann Jafar-nejad
Osama Al Dalahmah
Richard L. M. Faull
Clotilde Lagier-Tourenne
Affiliated Authors:
Osama Al Dalahmah
Publication Type:
Article
Unique ID:
10.1038/s41593-024-01850-w
PMID:
Publication Date:
Data Source:
Web of Science

Record Created: