Recovery of Conformational Continuum From Single-Particle Cryo-EM Images: Optimization of ManifoldEM Informed by Ground Truth

Seitz, E., Acosta-Reyes, F., Maji, S., Schwander, P., & Frank, J. (2022). Recovery of Conformational Continuum From Single-Particle Cryo-EM Images: Optimization of ManifoldEM Informed by Ground Truth. IEEE Transactions on Computational Imaging, 8, 462–478. https://doi.org/10.1109/tci.2022.3174801
Authors:
E. Seitz
F.J. Acosta-Reyes
Suvrajit Maji
Peter Schwander
Joachim Frank
Affiliated Authors:
E. Seitz
F.J. Acosta-Reyes
Suvrajit Maji
Joachim Frank
Columbia Affiliation:
Subjects:
Cryo-Electron Microscopy Techniques (OpenAlex Topic)
Advanced X-ray Imaging Techniques (OpenAlex Topic)
Atomic Force Microscopy Techniques (OpenAlex Topic)
Author Keywords:
biomolecules
free-energy landscape
kernel methods
manifold embedding
quantitative biology
single particle cryogenic microscopy (cryo-em)
spectral geometry
unsupervised machine learning
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Publication Type:
Article
Unique ID:
10.1109/tci.2022.3174801
PMID:
36258699
DOI:
10.1109/tci.2022.3174801
Journal:
IEEE Transactions on Computational Imaging
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: