Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

Remesh, S. G., Merz, G. E., Brilot, A. F., Chio, U. S., Rizo, A. N., Pospiech, T. H., Lui, I., Laurie, M. T., Glasgow, J., Le, C. Q., Zhang, Y., Diwanji, D., Hernandez, E., Lopez, J., Mehmood, H., Pawar, K. I., Pourmal, S., Smith, A. M., Zhou, F., … Verba, K. A. (2023). Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31(3), 253-264.e6. https://doi.org/10.1016/j.str.2023.01.009
Authors:
Soumya G Remesh
Gregory E Merz
Axel F Brilot
Un Seng Chio
Alexandrea N Rizo
Thomas H Pospiech
Irene Lui
Mathew T Laurie
Jeff Glasgow
Chau Q Le
Yun Zhang
Devan Diwanji
Evelyn Hernandez
Jocelyne Lopez
Hevatib Mehmood
Komal Ishwar Pawar
Sergei Pourmal
Amber M Smith
Fengbo Zhou
Joseph DeRisi
Tanja Kortemme
Oren S Rosenberg
Anum Glasgow
Kevin K Leung
James A Wells
Kliment A Verba
Affiliated Authors:
Anum Glasgow
Columbia Affiliation:
Subjects:
Angiotensin-Converting Enzyme 2 (MeSH)
COVID-19 (MeSH)
Author Keywords:
ace2 receptor traps
rosetta
sars-cov-2 omicron variant
spike
cryo-em
protein therapeutics
pseudovirus neutralization
elink
Publication Type:
Article
Unique ID:
10.1016/j.str.2023.01.009
PMID:
36805129
DOI:
10.1016/j.str.2023.01.009
Journal:
Structure
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record

Record Created: