Spns1 is an iron transporter essential for megalin-dependent endocytosis

Beenken, A., Shen, T., Jin, G., Ghotra, A., Xu, K., Nesanir, K., Sturley, R. E., Vijayakumar, S., Kahn, A., Levitman, A., Stauber, J., Chavez, E. Y., Robbins-Juarez, S. Y., Hao, L., Field, T. B., Erdjument-Bromage, H., Neubert, T. A., Shapiro, L., Qiu, A., & Barasch, J. (2024). Spns1 is an iron transporter essential for megalin-dependent endocytosis. American Journal of Physiology-Renal Physiology. https://doi.org/10.1152/ajprenal.00172.2024
Authors:
Andrew Beenken
Tian Shen
Guangchun Jin
Aryan Ghotra
Katherine Xu
Kivanc Nesanir
Rachel E Sturley
Soundarapandian Vijayakumar
Atlas Khan
Abraham Levitman
Jacob Stauber
Estefania Y Chavez
Shelief Y Robbins-Juarez
Luke Hao
Thomas B Field
Hediye Erdjument-Bromage
Thomas A Neubert
Lawrence Shapiro
Andong Qiu
Jonathan Barasch
Affiliated Authors:
Andrew Beenken
Tian Shen
Guangchun Jin
Aryan Ghotra
Katherine Xu
Rachel E Sturley
Soundarapandian Vijayakumar
Atlas Khan
Estefania Y Chavez
Luke Hao
Lawrence Shapiro
Jonathan Barasch
Columbia Affiliation:
Subjects:
Endocytosis (MeSH)
Low Density Lipoprotein Receptor-Related Protein-2 (MeSH)
Mice, Knockout (MeSH)
Kidney Tubules, Proximal (MeSH)
Cation Transport Proteins (MeSH)
Iron (MeSH)
Author Keywords:
endocytosis
iron
megalin
proteinuria
spns1
elink
Publication Type:
Article
Unique ID:
10.1152/ajprenal.00172.2024
PMID:
39265081
DOI:
10.1152/ajprenal.00172.2024
Journal:
American Journal of Physiology: Renal Physiology
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: