Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis

Neo, S. Y., Tong, L., Chong, J., Liu, Y., Jing, X., Oliveira, M. M. S., Chen, Y., Chen, Z., Lee, K., Burduli, N., Chen, X., Gao, J., Ma, R., Lim, J. P., Huo, J., Xu, S., Alici, E., Wickström, S. L., Haglund, F., … Lundqvist, A. (2024). Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis. Science Translational Medicine, 16(747). https://doi.org/10.1126/scitranslmed.adi2952
Authors:
Shi Yong Neo
Le Tong
Joni Chong
Yaxuan Liu
Xu Jing
Mariana M S Oliveira
Yi Chen
Ziqing Chen
Keene Lee
Nutsa Burduli
Xinsong Chen
Juan Gao
Ran Ma
Jia Pei Lim
Jianxin Huo
Shengli Xu
Evren Alici
Stina L Wickström
Felix Haglund
Johan Hartman
Arnika K Wagner
Yihai Cao
Rolf Kiessling
Kong Peng Lam
Lisa S Westerberg
Andreas Lundqvist
Affiliated Authors:
Yi Chen
Columbia Affiliation:
Subjects:
STAT3 Transcription Factor (MeSH)
Killer Cells, Natural (MeSH)
Interleukin-6 (MeSH)
Myeloid-Derived Suppressor Cells (MeSH)
Immune Tolerance (MeSH)
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Publication Type:
Article
Unique ID:
10.1126/scitranslmed.adi2952
PMID:
38748775
DOI:
10.1126/scitranslmed.adi2952
Journal:
Science Translational Medicine
Publication Date:
Data Source:
PubMed
Source Link:
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