Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity

Lydeard, J. R., Lin, M. I., Ge, H. G., Halfond, A., Wang, S., Jones, M. B., Etchin, J., Angelini, G., Xavier-Ferrucio, J., Lisle, J., Salvadore, K., Keschner, Y., Mager, H., Scherer, J., Hu, J., Mukherjee, S., & Chakraborty, T. (2023). Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity. Molecular Therapy - Methods & Clinical Development, 31, 101135. https://doi.org/10.1016/j.omtm.2023.101135
Authors:
John R Lydeard
Michelle I Lin
Huanying Gary Ge
Amanda Halfond
Shu Wang
Mark B Jones
Julia Etchin
Gabriella Angelini
Juliana Xavier-Ferrucio
Jessica Lisle
Kienan Salvadore
Yonina Keschner
Hannah Mager
Julian Scherer
Jianxin Hu
Siddhartha Mukherjee
Tirtha Chakraborty
Affiliated Authors:
Siddhartha Mukherjee
Author Keywords:
cd33
crispr-cas9
ind-enabled
acute myeloid leukemia
genome engineering
hematopoietic stem cell
immunotherapy
pharmacology/toxicology
Publication Type:
Article
Unique ID:
10.1016/j.omtm.2023.101135
PMID:
Publication Date:
Data Source:
PubMed

Record Created: